生物骨科材料与临床研究2025,Vol.22Issue(5):75-79,86,6.DOI:10.3969/j.issn.1672-5972.2025.05.014
脊柱结核动物模型的建立及研究进展
Establishment and research progress of animal model of spinal tuberculosis
夏远杰 1张慧浩 2冯晶 2浦飞飞 2夏平3
作者信息
- 1. 湖北中医药大学,湖北 武汉,430065||武汉市第一医院骨科,湖北 武汉,430022
- 2. 武汉市第一医院骨科,湖北 武汉,430022
- 3. 湖北中医药大学,湖北 武汉,430065||武汉市第四医院骨科,湖北 武汉,430033
- 折叠
摘要
Abstract
Spinal tuberculosis is a common extrapulmonary tuberculosis and a type of orthopedic disease that seriously threatens human health.The incidence of spine tuberculosis accounts for about 50%of bone and joint tuberculosis.There are still challenges in the current research on spinal tuberculosis:Its pathogenesis is still not fully understood,the treatment of patients with multi-drug-resistant tuberculosis,the treatment of tuberculosis combined with immune-related diseases,and the selection of implant materials.The use of animal models can circumvent the limitations of human ethical trial review and space-time constraints.There have been a large number of literature reports at home and abroad on various animal models of spinal tuberculosis.This article reviews the research progress and surgical modeling operations of spinal tuberculosis animal models by reviewing relevant domestic and foreign literature.关键词
结核/脊柱/疾病模型/动物Key words
Tuberculosis/Spinal/Disease models/Animal分类
医药卫生引用本文复制引用
夏远杰,张慧浩,冯晶,浦飞飞,夏平..脊柱结核动物模型的建立及研究进展[J].生物骨科材料与临床研究,2025,22(5):75-79,86,6.