山西中医药大学学报2025，Vol.26Issue(8)：873-877,888,6.DOI:10.19763/j.cnki.2096-7403.2025.08.08
补阳还五汤联合经刺激颅磁刺激治疗气虚血瘀型缺血性脑卒中偏瘫临床研究
Clinical study on Yang-Tonifying Five-Returning Decoction combined with transcranial mag-netic stimulation for hemiplegia after ischemic stroke with qi deficiency and blood stasis pattern
摘要
Abstract
Objective:To evaluate the clinical efficacy of Yang-Tonifying Five-Returning Decoction(Buyang Huanwu Tang)combined with transcranial magnetic stimulation(TMS)for hemiplegia after ischemic stroke manifesting qi deficiency and blood stasis pattern.Methods:Eighty-two patients with hemiplegia after ischemic stroke manifesting qi deficiency and blood stasis pattern were enrolled at the Rehabilitation Department of The Second Affiliated Hospital of Wannan Medical College from July 2022 to December 2023.Using simple randomization,patients were divided into control group(n=41,receiving TMS)and observation group(n=41,receiving TMS plus Yang-Tonifying Five-Returning Decoction).Both groups of pa-tients received conventional symptomatic treatment.Outcomes analyzed included TCM syndrome scores,walking capacity,Medical Research Council(MRC)muscle strength scale(upper limb),Fugl-Meyer Assessment(FMA)scores(lower limb),lower limb muscle strength,hemorheological indices,and adverse events.Results:Both groups showed significant improvement in all parameters post-treatment compared to baseline(P<0.05,P<0.01).The observation group demonstrated significantly lower TCM syndrome scores(hemilateral numbness,shortness of breath,fatigue,dark tongue coloration,sub-lingual varices)and hemorheological indices(low-shear whole blood viscosity,high-shear whole blood viscosity,erythrocyte aggregation index,fibrinogen),superior walking capacity(6-minute walk distance,10-meter walk time),higher MRC scores(upper limb),FMA scores(lower limb),and muscle strength(hip extension,knee extension,ankle dorsiflexion)compared to controls(P<0.05,P<0.01).No adverse reactions occurred in either group.Conclusion:Combined Yang-Tonifying Five-Returning Decoction and TMS improves neurological function,enhances motor performance and ambulation capacity,regulates hemorheology,and provides superior holistic symptom relief compared to transcranial magnetic stimula-tion alone,offering an integrated approach for hemiplegia after ischemic stroke with qi deficiency and blood stasis pattern.关键词
缺血性脑卒中/偏瘫/补阳还五汤/经颅磁刺激Key words
ischemic stroke/hemiplegia/Yang-Tonifying Five-Returning Decoction/transcranial magnetic stimulation分类
医药卫生引用本文复制引用
何胜飞,张金琴,李杜娟,李文,李扬缜..补阳还五汤联合经刺激颅磁刺激治疗气虚血瘀型缺血性脑卒中偏瘫临床研究[J].山西中医药大学学报,2025,26(8):873-877,888,6.基金项目
芜湖市卫生健康委科研项目(WHWJ2023z006) （WHWJ2023z006）
