上海预防医学2025，Vol.37Issue(8)：663-668,6.DOI:10.19428/j.cnki.sjpm.2025.24687
重庆市一起成人A组G9P[8]型轮状病毒感染性腹泻暴发疫情调查
Investigation of an outbreak of group A human G9P[8]rotavirus infectious diarrhea among adults in Chongqing
摘要
Abstract
[Objective]To investigate and analyze an outbreak of rotavirus infectious diarrhea in a prison in Chongqing Municipality,to provide a basis for adult rotavirus surveillance and prevention,and to explore the public health problems in special settings.[Methods]A retrospective survey was conducted to collect and analyze data on individual cases with diarrheal disease on-site.The clinical characteristics,as well as the temporal,spatial and geographical distribution patterns of the epidemic were described.Multi-pathogen detection tests were conducted both on diarrhea cases and environmental samples,with viral genotyping performed on positive samples.A case-control analysis was performed to identify the causes of the outbreak,and an SEIR model was adopted to predict the outbreak trend and evaluate the effectiveness of interventions.[Results]A total of 65 cases were found among the inmates,with an attack rate of 2.03%.The predominant clinical manifestations included diarrhea(89.23%),watery stool(73.85%),and dehydration(18.46%).The epidemic curve indicated a"human-to-human"transmission pattern,with an average incubation period of 5‒6 days.The attack rates among chefs in the main canteen(80.00%,8/10)and caterers(28.33%,17/60)were significantly higher than those of other inmates(P<0.05).Multi-pathogen polymerase chain reaction(PCR)testing detected positive for group A rotavirus,with the viral genotyping identified as G9P[8]strain.Factors such as unprotected"bare-handed"food distribution among cases with diarrhea(OR=9.512,95%CI:4.261‒21.234)and close contact with diarrhea cases(OR=3.656,95%CI:1.719‒7.778)were the possible cause of the outbreak.The SEIR model(r0=5,α=0.3,β1=0.08,β2=0.04)was constructed using prison inmates as susceptible population,aiming at fitting the initial transmission trend of the outbreak,and the epidemic rate declined rapidly after intervention measures were implemented(rt≈0).[Conclusion]This rare rotavirus infection diarrhea outbreak among adults in confined settings suggests that the construction of public health prevention and control systems in prison may be overlooked.Cross infection during meal processing and distribution in the canteens of such settings is likely to be the cause of the outbreak.Given the potential neglect of public heath system construction in special settings,it is imperative to enhance the surveillance and monitoring of rotavirus and other intestinal multi-pathogens among adults,as well as the construction of public health prevention and control systems in these special settings.关键词
轮状病毒/感染性腹泻/监管场所/暴发疫情Key words
rotavirus/infectious diarrhea/correctional facility/outbreak of epidemic分类
医药卫生引用本文复制引用
王洋,卢洁,肖权倢,巴莹莹,吴汶禧,徐茜,闫菊,孔源,陈宁,杨纶砥,龙江,李勤,徐晓阳,郑伟,韦红..重庆市一起成人A组G9P[8]型轮状病毒感染性腹泻暴发疫情调查[J].上海预防医学,2025,37(8):663-668,6.基金项目
重庆市卫生健康委员会科研项目(2025WSJK095) （2025WSJK095）
重庆市公共卫生重点专(学)科建设项目 （学）
重庆市南川区科学技术局科技计划项目(Cx202308) （Cx202308）
重庆市沙坪坝区2023年度技术创新与应用发展项目(202304) （202304）
