畜牧兽医学报2025，Vol.56Issue(9)：4204-4214,11.DOI:10.11843/j.issn.0366-6964.2025.09.007
热应激通过干扰生物钟系统影响反刍动物消化道屏障功能的研究进展
Research Progress of Heat Stress Affect Digestive Tract Barrier Function of Ruminants by Interfering with Biological Clock
摘要
Abstract
In recent years,as the global greenhouse effect has become more serious,frequent extreme weather has caused huge economic losses to animal husbandry.Especially in the summer when heat waves are frequent,continuous high temperatures can cause heat stress reactions in ruminants,resulting in stunted growth and development,increased mortality,and serious restrictions on the high-quality development of animal husbandry.Studies have found that heat stress has a particularly significant impact on the intestinal health of young ruminants,causing disordered intestinal microbial flora structure,oxidative stress damage,and increased barrier permeability.However,most existing studies only explore intestinal damage caused by heat stress at a single time point,but the latest research reveals that intestinal barrier function is not static but shows circadian rhythmic changes.To this end,this article reviews the effects of heat stress on the circadian rhythm of the digestive tract biological clock and barrier function of ruminants on a diurnal time scale,in order to find potential pathways and mechanisms for heat stress to regulate digestive tract barrier function through the biological clock,and provide new ideas for precise production and environmental management of ruminants.关键词
热应激/生物钟/消化道屏障Key words
heat stress/biological clock/digestive tract barrier分类
农业科技引用本文复制引用
易唤明,鲍国升,万辉,欧靖渝,何小龙,任春环,陈家宏,张子军,王强军..热应激通过干扰生物钟系统影响反刍动物消化道屏障功能的研究进展[J].畜牧兽医学报,2025,56(9):4204-4214,11.基金项目
国家自然科学基金青年项目(32302802) （32302802）
国家重点研发计划"山羊湖羊新品种新品系培育及良种扩繁"(2022YFD1300202) （2022YFD1300202）
青海省高寒草地适应性管理重点实验室开放基金课题(2023-GHSYS-KF-04) （2023-GHSYS-KF-04）
安徽省高校自然科学研究重点项目(2023AH051037) （2023AH051037）
国家肉羊产业技术体系(CARS-38) （CARS-38）
