医药导报2025，Vol.44Issue(10)：1562-1565,4.DOI:10.3870/j.issn.1004-0781.2025.10.006
1例肾移植术后螺内酯相关性无症状高尿酸血症的诊断与治疗
Diagnosis and Treatment of a Case of Spironolactone-Associated Asymptomatic Hyperuricemia After Renal Transplantation
摘要
Abstract
Objective To explore the identification method,pathogenesis,clinical characteristics and individualized pharmacotherapy of asymptomatic hyperuricemia after renal transplantation.Methods The pharmacist was on duty at the organ transplant outpatient clinic.During this time,they analyzed and sorted out the medications,identified and differentiated a case of asymptomatic hyperuricemia related to spironolactone in a patient who had undergone a renal transplant,and provided comprehensive care throughout the entire process.Results The asymptomatic hyperuricemia in this patient might be associated with spironolactone,and the adverse reactions of the patient were alleviated by pharmacists through optimizing clinical treatment.Up to now,no hyperuricemia occurred.Conclusions Pharmacists are required to collaborate closely with clinicians to establish medication profiles for patients under long-term follow-up and to closely monitor and evaluate drug-related adverse reactions.Additionally,they should assess the renal function and immune status of transplant recipients promptly and formulate individualized treatment plans in order to enhance the long-term survival of both the transplanted kidneys and the recipients.关键词
螺内酯/肾移植/高尿酸血症/个体化用药Key words
Spironolactone/Renal transplantation/Hyperuricemia/Individualized medicine分类
医药卫生引用本文复制引用
肖云,姜正尧,邹晟,杜安乐,李国惠,郭晓晖,钟林,何佳珂,韩晓雨,郑超,傅毓,熊寒斌,邹斌,汪保林,邹华,尹成龙..1例肾移植术后螺内酯相关性无症状高尿酸血症的诊断与治疗[J].医药导报,2025,44(10):1562-1565,4.基金项目
国家自然科学基金资助项目(82160707、82060677) （82160707、82060677）
江西省自然科学基金青年重点项目(20202ACB216005) （20202ACB216005）
江西省主要学科学术和技术带头人培养计划-青年人才项目(20204BCJL23053) （20204BCJL23053）
南昌大学第二附属医院院内资助项目(2022efyB04) （2022efyB04）
江西省自然科学基金面上项目(20224BAB206105). （20224BAB206105）
