中国临床药理学与治疗学2025，Vol.30Issue(9)：1272-1280,9.DOI:10.12092/j.issn.1009-2501.2025.09.014
槲皮素防治急性肺损伤作用机制的研究进展
Research progress on the mechanism of quercetin in preventing and treating acute lung injury
摘要
Abstract
Acute lung injury is an acute and criti-cal respiratory disease with complex pathogenesis,which has a high incidence rate and high mortality.At present,acute lung injury is mainly treated by mechanical ventilation,glucocorticoid anti-inflam-matory and extracorporeal membrane oxygen-ation.Traditional Chinese medicine also shows great potential in improving the clinical manifesta-tions and prognosis of patients.Quercetin is a fla-vonol compound,which can prevent and treat acute lung injury by anti-inflammatory,anti-oxida-tive stress,regulating programmed cell death,anti-bacterial and antiviral.This article summarizes the mechanism of action and research progress of quercetin in the treatment of acute lung injury,aiming to provide reference for subsequent re-search and clinical applications.关键词
槲皮素/急性肺损伤/抗炎/抗氧化应激/铁死亡Key words
quercetin/acute lung injury/anti-in-flammatory/anti-oxidant stress/ferroptosis分类
医药卫生引用本文复制引用
林艺燕,吴月莹,严锐,吴东..槲皮素防治急性肺损伤作用机制的研究进展[J].中国临床药理学与治疗学,2025,30(9):1272-1280,9.基金项目
广东省自然科学基金(2022A1515011731) （2022A1515011731）
