中国比较医学杂志2025，Vol.35Issue(9)：122-133,12.DOI:10.3969/j.issn.1671-7856.2025.09.012
针刺促进脑出血神经重塑机制研究进展
Research progress into the role of acupuncture in promoting neurological remodeling after intracerebral hemorrhage
摘要
Abstract
Neural remodeling is the key to neurological recovery after intracerebral hemorrhage(ICH).The early stage of stroke is a sensitive period for brain plasticity,during which the brain initiates complex processes such as neurogenesis,synaptic remodeling,and angiogenesis to promote collateral circulation and achieve structural and functional remodeling.Acupuncture,as a critical traditional Chinese medicine approach for treating brain disorders,has demonstrated significant efficacy in promoting neurological recovery after ICH in both clinical and experimental studies;however,systematic reviews of the mechanisms by which acupuncture regulates neural remodeling after ICH remain limited.This review thus provides a multi-dimensional summary of the mechanisms by which acupuncture facilitates neural remodeling after ICH,including(1)promoting neurogenesis and synaptic remodeling;(2)modulating the damaged microenvironment;(3)optimizing neuroelectrophysiology;(4)improving hemodynamics;(5)facilitating angiogenesis.This review systematically summarizes these mechanisms to highlight the therapeutic potential of acupuncture and advance its further research and application in the field of neuroscience.关键词
针刺/脑出血/神经重塑/神经再生/神经发生/神经可塑性Key words
acupuncture/intracerebral hemorrhage/neural remodeling/neuro regeneration/neurogenesis/neuroplasticity分类
医药卫生引用本文复制引用
董珊珊,罗恩丽..针刺促进脑出血神经重塑机制研究进展[J].中国比较医学杂志,2025,35(9):122-133,12.基金项目
深圳市科技计划资助项目(JCYJ20240813144017023) （JCYJ20240813144017023）
国家自然科学基金项目(82374567) （82374567）
广东省自然科学基金(2023A1515012779) （2023A1515012779）
"深圳市医疗卫生三名工程"项目(SZZYSM202411004). （SZZYSM202411004）
