中国实用妇科与产科杂志2025，Vol.41Issue(9)：879-883,5.DOI:10.19538/j.fk2025090104
产后溶血尿毒症综合征:发病机制与多学科诊疗新视角
Postpartum hemolytic uremic syndrome:pathogenesis and new perspective of multidisciplinary diagnosis and treatment
摘要
Abstract
Postpartum hemolytic uremic syndrome refers to a serious life-threatening syndrome characterized by acute microvascular hemolytic anemia,thrombocytopenia,and acute renal failure that occurs after childbirth.If not treat-ed,it will lead to a mortalityrate of up to 90％.The etiology is still unknown.Current research suggests that endothelial dysfunction,coagulation fibrinolysis imbalance,and abnor-mal activation of the complement system are the main pathogenesis of this syndrome.Although the incidence is ex-tremely low,the mortality rate is high and the treatment op-tions are limited.In recent years,with the deepening of re-search on the complement system,new treatment methods such as complement inhibitors have brought new hope to PHUS patients.This article elaborates and discusses its pathogenesis,diagnosis and treatment.关键词
产后溶血尿毒症综合征/溶血性贫血/血小板减少/肾功能衰竭/多学科团队Key words
postpartum hemolytic uremic syndrome/hemolytic anemia/thrombocytopenia/renal failure/MDT分类
医药卫生引用本文复制引用
杨海澜,韩玉..产后溶血尿毒症综合征:发病机制与多学科诊疗新视角[J].中国实用妇科与产科杂志,2025,41(9):879-883,5.基金项目
Science and Technology Research Proj-ect of Shanxi Provincial Department of Science and Tech-nology(YDZJSX2022B010) 山西省科技厅科技攻关项目(YDZJSX2022B010) （YDZJSX2022B010）
