中国实用妇科与产科杂志2025，Vol.41Issue(9)：883-886,4.DOI:10.19538/j.fk2025090105
HELLP综合征和产后溶血尿毒症综合征的鉴别诊断
Differential diagnosis between HELLP syndrome and postpartum hemolytic uremic syndrome
摘要
Abstract
The accurate diagnosis and prompt management of pregnancy-associated complications are crucial for safe-guarding the well-being of both mothers and infants.This is particularly true for diseases presenting with similar clini-cal manifestations yet having markedly distinct treatment strategies.The HELLP syndrome(characterized by hemoly-sis,elevated liver enzymes,and thrombocytopenia)and postpartum hemolytic uremic syndrome(PHUS),as typical examples of pregnancy-related thrombotic microangiopathy(TMA),share comparable clinical features but possess fun-damental pathological disparities.Both diseases have an in-sidious onset and progress rapidly,and misdiagnosis or de-layed diagnosis is not uncommon,which significantly com-promises patient prognosis.Thus,the accurate discrimina-tion between the HELLP syndrome and PHUS is pivotal for enhancing diagnostic and therapeutic efficacy and reducing maternal mortality.This article comprehensively analyzes the similarities and differences in the pathogenesis,clini-cal characteristics,and laboratory findings of the two con-ditions.It proposes a differential diagnosis approach based on multidisciplinary cooperation and underlines the signifi-cance of early recognition in improving prognosis.By re-viewing the latest domestic and international guidelines and clinical practices,key differential diagnostic points are summarized,aiming to offer a reference for clinical de-cision-making.关键词
HELLP综合征/产后溶血尿毒症综合征/鉴别诊断/血栓性微血管病/妊娠并发症Key words
HELLP syndrome/postpartum hemolytic uremic syndrome/differential diagnosis/thrombotic microangiopathy/pregnancy complications分类
医药卫生引用本文复制引用
赵先兰,陶雅..HELLP综合征和产后溶血尿毒症综合征的鉴别诊断[J].中国实用妇科与产科杂志,2025,41(9):883-886,4.基金项目
Henan Provincial Medical Science and Technology Research Project(201602102) 河南省医学科技攻关项目(201602102) （201602102）
