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脊柱关节炎结局异质性及治疗个体化

黄天雯 刘毅

中国实用内科杂志2025,Vol.45Issue(9):717-721,5.
中国实用内科杂志2025,Vol.45Issue(9):717-721,5.DOI:10.19538/j.nk2025090101

脊柱关节炎结局异质性及治疗个体化

Heterogeneity of outcomes and individualized treatment for spondyloarthritis

黄天雯 1刘毅1

作者信息

  • 1. 四川大学华西医院风湿免疫科,四川成都 610041
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摘要

Abstract

Spondyloarthritis(SpA)represents a group of complex inflammatory disorders,among which ankylosing spondylitis(AS)is the most representative subtype.Heterogeneous outcomes in SpA are significantly driven by high rates of misdiagnosis due to ambiguities in current classification/diagnostic criteria,substantial inter-patient heterogeneity,and the complex,multifaceted pathogenesis of the disease.Consequently,implementing individualized precision medicine approaches is crucial for effective long-term disease management.Future diagnostic and therapeutic endeavors should focus on refining early classification criteria,developing comprehensive disease management strategies tailored to patient characteristics,and leveraging big data technology to establish precision treatment protocols,aiming to improve prognosis and enhance quality of life of the patients.

关键词

脊柱关节炎/预后/异质性/个体化治疗

Key words

spondyloarthritis/prognosis/heterogeneity/individualized treatment

分类

医药卫生

引用本文复制引用

黄天雯,刘毅..脊柱关节炎结局异质性及治疗个体化[J].中国实用内科杂志,2025,45(9):717-721,5.

中国实用内科杂志

OA北大核心

1005-2194

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