中国全科医学2025，Vol.28Issue(34)：4337-4343,7.DOI:10.12114/j.issn.1007-9572.2024.0489
2016-2022年乌鲁木齐市慢性病患者共病及复杂共病流行情况与共病模式研究
The Prevalence of Multimorbidity and Complex Multimorbidity in Patients with Chronic Diseases and Patterns in Urumqi City,2016-2022
摘要
Abstract
Background Currently,the prevalence of multimorbidity among patients with chronic diseases in China is increasing,resulting in a growing burden of disease.However,research on complex multimorbidity is relatively limited in China,underscoring an urgent need for a substantial body of evidence to inform the development of comprehensive and coordinated strategies for the control of persistent impacts of multimorbidity and complex multimorbidity.Objective The present study aims to investigate the prevalence of,and patterns of,multimorbidity and complex multimorbidity among patients with chronic diseases in Urumqi City between 2016 and 2022.Methods In June 2023,a comprehensive data set encompassing general demographic information and the prevalence of chronic diseases among patients with 27 chronic diseases was retrieved from the Urumqi City Public Health Surveillance Database and Electronic Medical Record Information Database from 2016 to 2022.The prevalence trends of multimorbidity(suffering from≥2 chronic diseases)and complex multimorbidity(suffering from≥3 chronic diseases)in patients with chronic diseases were analyzed.Multifactorial logistic regression was used to This analysis sought to elucidate the factors that influence the occurrence of both chronic disease multimorbidity and complex multimorbidity.Additionally,the Apriori association rule algorithm was employed to identify the common patterns underlying chronic disease multimorbidity and complex multimorbidity.Results A total of 45 150 cases of study subjects were included during the seven-year period,comprising 12 969(28.72%)cases of patients with a single chronic disease and 27 992(62.00%)cases of patients with Additionally,4 189 cases(9.28%)were identified as patients with complex multimorbidity,and the mean number of concomitant diseases per patient increased from(1.73±0.86)to(2.56±1.15).The results of the multifactorial Logistic regression analysis indicated that advancing age,male gender,and urban residence were significant risk factors for the development of comorbidities and complex multimorbidity in patients with chronic diseases.Of the 27 chronic diseases included in the study,the top three chronic disease prevalence rates were 33 675 cases of hypertension(74.58%),32 942 cases of dyslipidemia(72.96%)and 12 408 cases of diabetes mellitus(27.48%).The most common binary co-morbidity patterns were"dyslipidemia+hypertension""diabetes+hypertension"and"diabetes+dyslipidemia".The most common ternary co-morbidity patterns were"dyslipidemia+diabetes mellitus+hypertension""oronary heart disease+dyslipidemia+hypertension"and"dyslipidemia+renal cyst+hypertension".Coronary heart disease was the preceding disease in all directional association rules.All rules appeared as antecedent diseases.The circulatory system was the most common co-occurring system,and the antecedents of several association rules directed to the circulatory system were all related to the endocrine system.Conclusion The prevalence of chronic disease multimorbidity and complex multimorbidity in Urumqi City has been increasing annually,with age,gender,and urban/rural differences playing a significant role.Hypertension,dyslipidemia,and diabetes mellitus are the most prevalent multimorbidity,while the most affected organ systems are the circulatory,digestive,and endocrine systems.The most common aggregation pattern is cardiometabolic disease.关键词
慢性病共病/复杂共病/关联规则/共病模式Key words
Multimorbidity/Complex multimorbidity/Association rule/Multimorbidity pattern分类
医药卫生引用本文复制引用
周燚然,苏银霞,殷峰,武云,古丽加衣娜·艾肯,卢耀勤..2016-2022年乌鲁木齐市慢性病患者共病及复杂共病流行情况与共病模式研究[J].中国全科医学,2025,28(34):4337-4343,7.基金项目
新疆维吾尔自治区自然科学基金杰出青年科学基金项目(2024D01E29) （2024D01E29）
新疆维吾尔自治区研究生科研创新项目(XJ2024G170) （XJ2024G170）
