中国医学创新2025，Vol.22Issue(28)：24-27,4.DOI:10.3969/j.issn.1674-4985.2025.28.006
金水宝片辅助治疗艾滋病合并肺结核对HIV-RNA载量及CD4+T细胞的影响
Effect of Jinshuibao Tablets on HIV-RNA Load and CD4+T Cells in Adjuvant Treatment of AIDS Complicated with Pulmonary Tuberculosis
摘要
Abstract
Objective:To investigate the effect of Jinshuibao Tablets on HIV-RNA load and CD4+T cells in adjuvant treatment of AIDS patients complicated with pulmonary tuberculosis.Method:A total of 105 cases of AIDS patients complicated with pulmonary tuberculosis admitted to the Fifth People's Hospital of Ganzhou from January 2022 to January 2024 were selected.According to the random number table,the patients were divided into two groups:the control group(n=52)and the observation group(n=53).The control group was treated with conventional western medicine(highly effective antiretroviral+antituberculosis program),and the observation group was treated with Jinshuibao Tablets on this basis.The clinical efficacy,differences in HIV-RNA load,CD4+T cell count levels before and after treatment,and incidence of adverse drug reactions between two groups were compared.Result:The total effective rate of the observation group was 94.34%(50/53),while the control group was 78.85%(41/52),the total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The HIV-RNA load of both groups of patients after 1 month and 6 months of treatment decreased compared to those before treatment,while the CD4+T cell count increased compared to those before treatment,with statistically significant differences(P<0.05);moreover,the HIV-RNA load and CD4+T cell count in the observation group were lower and higher than those in the control group after 1 month and 6 months of treatment,with statistically significant differences(P<0.05).During the treatment period,the incidence of adverse reactions in the observation group was 9.43%(5/53),while in the control group was 7.69%(4/52),there was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Jinshuibao Tablets is effective in the adjuvant treatment of AIDS patients complicated with pulmonary tuberculosis,it can effectively reduce the HIV-RNA load of patients,improve the immune function of the body,and has good drug safety.关键词
艾滋病/肺结核/金水宝片/HIV-RNA载量/CD4+T细胞Key words
AIDS/Tuberculosis/Jinshuibao Tablets/HIV-RNA load/CD4+T cells引用本文复制引用
王培兴,彭海英,孙玉霞,曾江..金水宝片辅助治疗艾滋病合并肺结核对HIV-RNA载量及CD4+T细胞的影响[J].中国医学创新,2025,22(28):24-27,4.基金项目
江西省中医院管理局科技计划课题(2022B1077) （2022B1077）
