中国医学创新2025，Vol.22Issue(27)：1-5,5.DOI:10.3969/j.issn.1674-4985.2025.27.001
健脾生血颗粒联合右旋糖酐铁治疗妊娠期缺铁性贫血的效果
Effect of Jianpi Shengxue Granules Combined with Iron Dextran in the Treatment of Iron Deficiency Anemia during Pregnancy
摘要
Abstract
Objective:To evaluate the clinical efficacy of Jianpi Shengxue Granules combined with Iron Dextran in patients with iron deficiency anemia during pregnancy.Method:The study was conducted from January 2021 to January 2024.100 patients with iron deficiency anemia during pregnancy admitted to Fuzhou Maternal and Child Health Hospital were included.The patients were divided into the experimental group and the control group by the random number table method,with 50 cases in each group.The control group received Iron Dextran treatment,and the experimental group received Jianpi Shengxue Granules combined with Iron Dextran treatment.Both groups were treated continuously for 4 weeks.The improvement of symptoms(sallow complexion,fatigue,dizziness,reduced appetite),therapeutic effect,blood routine[RBC,Hb,mean corpuscular volume(MCV),mean corpuscular hemoglobin concentration(MCHC)],iron metabolism[serum ferritin(SF),serum iron(SI),hepcidin(HEPC),transferrin(TRF),transferrin(TS)and total iron binding capacity(TIBC)],adverse reactions(abdominal pain and diarrhea,nausea and vomiting,rash,constipation),adverse pregnancy outcomes(premature birth,premature rupture of membranes,neonatal asphyxia,postpartum hemorrhage,puerperal infection)between the two groups were compared.Result:The improvement time of sallow complexion,fatigue,dizziness and reduced appetite in the experimental group were earlier than those in the control group(P<0.05).The total effective rate of the experimental group was higher than that of the control group(P<0.05).After treatment,the RBC,Hb,MCV and MCHC in the experimental group were higher than those in the control group(P<0.05).After treatment,TIBC and TRF in the experimental group were lower than those in the control group,while SF,SI,HEPC and TS were higher than those in the control group(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The total incidence of adverse pregnancy outcomes in the experimental group was lower than that in the control group(P<0.05).Conclusion:The combination of Jianpi Shengxue Granules and Iron Dextran in the treatment of iron deficiency anemia during pregnancy can more effectively improve the symptoms,blood routine indicators and iron metabolism indicators of patients,reduce the occurrence of adverse pregnancy outcomes,and has high safety.关键词
健脾生血颗粒/右旋糖酐铁/妊娠期缺铁性贫血/铁代谢Key words
Jianpi Shengxue Granules/Iron Dextran/Iron deficiency anemia during pregnancy/Iron metabolism引用本文复制引用
董桂生,黎建琴..健脾生血颗粒联合右旋糖酐铁治疗妊娠期缺铁性贫血的效果[J].中国医学创新,2025,22(27):1-5,5.基金项目
抚州市指导性科技计划项目(抚科社字[2024]1号序号21) （抚科社字[2024]1号序号21）
