中国中医急症2025，Vol.34Issue(9)：1474-1478,5.DOI:10.3969/j.issn.1004-745X.2025.09.007
心源性休克中医证型分布与病情严重程度及预后的相关性分析
Correlation Analysis between Distribution of Traditional Chinese Medicine Syndrome Patterns,Disease Severity,and Prognosis in Patients with Cardiogenic Shock
摘要
Abstract
Objective:To investigate the distribution characteristics of Traditional Chinese medicine(TCM)syn-drome patterns in cardiogenic shock(CS)and their correlations with disease severity,cardiac function,and progno-sis.Methods:A retrospective study was conducted on 432 CS patients admitted to Guangdong Provincial Hospi-tal of Chinese Medicine from June 2019 to June 2024.Among them,273 were diagnosed with syndrome of sudden collapse of heart yang,and 159 with non-syndrome of sudden collapse of heart yang(including 82 with syndrome of qi-yin deficiency and 77 with syndrome of qi stagnation and blood stasis).Data collected included general infor-mation,four-diagnostic-method data,TCM syndrome patterns,shock stage,blood lactate and serum NT-proBNP levels,liver and kidney function,left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular fractional shortening(LVFS),shock in-dex(SI),CardShock score,type and duration of vasoactive drugs and mechanical circulatory support,length of hos-pital stay and total cost,incidence of cardiac arrest,28-day mortality,and within one year after discharge,readmis-sion rate and incidence of major adverse cardiovascular events(MACE)in survivors.Spearman correlation analysis was used to examine the relationships between syndrome of sudden collapse of heart yang and disease severity,car-diac function,and prognosis.Results:Compared with the non-syndrome of sudden collapse of heart yang group,the syndrome of sudden collapse of heart yang group had significantly higher levels of lactate,NT-proBNP,renal function indicators,LVESD,SI,CardShock score,total hospitalization cost,intensity of vasoactive drugs and me-chanical support,incidence of cardiac arrest,28-day mortality,one-year readmission rate,and MACE incidence in survivors(P＜0.05).Conversely,LVEF and LVFS levels were significantly lower in the syndrome of sudden col-lapse of heart yang group(P＜0.05).Disease severity showed a positive correlation with syndrome of sudden col-lapse of heart yang(P＜0.05),while cardiac function and prognosis showed a negative correlation with this syn-drome(P＜0.05).Conclusion:Syndrome of sudden collapse of heart yang in CS may be closely associated with disease severity,cardiac function,and prognosis.关键词
心源性休克/心阳暴脱证/病情严重程度/心功能/预后Key words
Cardiogenic shock/Syndrome of sudden collapse of heart yang/Disease severity/Cardiac function/Prognosis分类
医药卫生引用本文复制引用
聂昊,徐于浩,戴杏珍,庄杰钦..心源性休克中医证型分布与病情严重程度及预后的相关性分析[J].中国中医急症,2025,34(9):1474-1478,5.基金项目
国家自然科学基金项目(82074342) （82074342）
广东省中医药局科研项目(20254047) （20254047）
广东省中医院中医药科学技术研究专项课题(YN2023QN19) （YN2023QN19）
