中国中医急症2025，Vol.34Issue(9)：1483-1486,4.DOI:10.3969/j.issn.1004-745X.2025.09.009
从"伏邪"与"毒邪"探讨难治性哮喘的证治
Exploration of Syndrome Differentiation and Treatment of Refractory Asthma from the Perspectives of"Hidden Pathogen"and"Toxic Pathogen"
摘要
Abstract
This paper explores the diagnosis and treatment of refractory asthma based on the concepts of"hid-den pathogen"and"toxic pathogen".It suggests that the key pathogenic mechanism during acute exacerbation is"hidden pathogens transforming into toxin,leading to dysfunction in lung dispersion and descent".In the chronic persistent phase,the main pathogenesis involves"lingering toxin obstructing qi circulation,"while in the remission stage,it is characterized by"phlegm and blood stasis blocking together with residual pathogenic factors lying dor-mant under deficiency."In terms of therapeutic strategies:during the acute exacerbation stage,the primary treat-ment principle focuses on"detoxifying,resolving turbidity,regulating lung function,and relieving asthma."The method emphasizes treating both lung and stomach simultaneously.Maxing Shigan Decoction combined with Shengjiang Powders is recommended as the representative formula.For patients with severe cough and excessive phlegm,the approach of"descending rebellious qi,resolving phlegm,detoxifying,and relieving asthma"is adopted,using Zeqi Decoction as the main prescription.In the chronic persistent stage,the treatment aims at eliminating re-sidual toxicity and promoting smooth qi movement.The therapeutic strategy includes"promoting dispersion and de-scent,diuresis,activating blood circulation,and detoxification,"using Dachaihu Decoction combined with Danggui Shaoyao Powders.During the remission stage,the emphasis lies on"strengthening the body's resistance,removing pathogenic factors,and avoiding triggers"to prevent recurrence.The selection of herbs is flexibly adjusted accord-ing to the degree of involvement of the lung,spleen,kidney,and phlegm stasis caused by excessive pathogen.关键词
难治性哮喘/伏邪/毒邪/中西医结合/急诊学Key words
Refractory asthma/Hidden pathogen/Toxic pathogen/Integrated traditional Chinese and Western medicine/Emergency medicine分类
医药卫生引用本文复制引用
赵春铭,胡聿昕,李昀泽,王宇琛,徐霄龙,陈腾飞,刘清泉..从"伏邪"与"毒邪"探讨难治性哮喘的证治[J].中国中医急症,2025,34(9):1483-1486,4.基金项目
国家自然科学基金项目(82141202) （82141202）
国家中医药多学科交叉创新团队项目(ZYYCXTD-D-202201) （ZYYCXTD-D-202201）
