针灸临床杂志2025，Vol.41Issue(9)：1-7,7.DOI:10.19917/j.cnki.1005-0779.025166
高通量组学技术在针灸中的应用及展望
Application and Prospects of High-Throughput Omics Technology in Acupuncture
摘要
Abstract
Objective:As a conventional therapeutic approach,acupuncture is an indispensable component of TCM.However,due to the lack of systematic biological validation,our understanding of its underlying mechanisms remains limited.The emergence and advancement of high-throughput omics technologies have provided new tools and theoretical support for elucidating the biological basis of acupuncture.Unlike traditional linear pathway-based studies,systematic biology approaches enable comprehensive analysis of acupuncture's effects on the organism.This review explores the integration of acupuncture with various omics techniques,including genomics,proteomics,metabolomics,and multi-omics integration at the tissue level,as well as single-cell sequencing and spatial transcriptomics at the cellular level.It provides an in-depth discussion on the mechanisms of acupoint activation,signal transduction,and target organ effects.These studies enhance the understanding of acupuncture at both molecular and cellular levels,offering a scientific foundation for its further development and application in modern medicine.关键词
针灸/高通量组学/代谢组学/蛋白质组学/转录组学Key words
Acupuncture/High-throughput omics/Metabonomics/Proteomics/Transcriptomics分类
医药卫生引用本文复制引用
王江山,徐枝芳,郭义,樊泽至,姚开芳,窦报敏,李艳伟,陈志翰,付疆疆,杜思敏,吴勇箭..高通量组学技术在针灸中的应用及展望[J].针灸临床杂志,2025,41(9):1-7,7.基金项目
国家自然科学基金重点项目,编号:82030125. （）
