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首页|期刊导航|中外医学研究|静注人免疫球蛋白辅助治疗新生儿肺炎的疗效及对炎症反应的影响

静注人免疫球蛋白辅助治疗新生儿肺炎的疗效及对炎症反应的影响

陈嘉芳

中外医学研究2025,Vol.23Issue(25):45-47,3.
中外医学研究2025,Vol.23Issue(25):45-47,3.DOI:10.14033/j.cnki.cfmr.2025.25.013

静注人免疫球蛋白辅助治疗新生儿肺炎的疗效及对炎症反应的影响

Efficacy of Adjuvant Treatment of Neonatal Pneumonia with Intravenous Human Immunoglobulin and its Effect on Inflammatory Response

陈嘉芳1

作者信息

  • 1. 莆田市儿童医院 福建 莆田 351100
  • 折叠

摘要

Abstract

Objective:To observe the efficacy of intravenous human immunoglobulin as an adjuvant treatment for neonatal pneumonia and its influence on inflammatory response.Method:According to the random number table method,86 children with pneumonia admitted to Putian Children's Hospital from June 2022 to October 2024 were divided into two groups,with 43 cases in each group.The control group received conventional treatment.On this basis,the observation group was intravenously injected with human immunoglobulin as an adjuvant treatment for 7 days.The therapeutic effects,symptom improvement time,inflammatory factors[white blood cell count(WBC),procalcitonin(PCT),C-reactive protein(CRP)]and adverse reactions of the two groups were compared.Result:After treatment,compared with the control group,the observation group had a higher total effective rate,fever reduction,cough disappearance,shorter hospital stay,and lower levels of serum WBC,PCT and CRP.The differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Intravenous human immunoglobulin as an adjuvant therapy can improve the clinical efficacy of children with neonatal pneumonia,reduce inflammatory responses,promote the recovery process,shorten the length of hospital stay,and has high safety.

关键词

新生儿肺炎/人免疫球蛋白/疗效/炎症反应

Key words

Neonatal pneumonia/Human immunoglobulin/Efficacy/Inflammatory response

引用本文复制引用

陈嘉芳..静注人免疫球蛋白辅助治疗新生儿肺炎的疗效及对炎症反应的影响[J].中外医学研究,2025,23(25):45-47,3.

中外医学研究

1674-6805

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