首页|期刊导航|中医药科学（英文）|Pharmacokinetics,tissue distribution,and excretion of anthraquinones and their glucuronide metabolites from raw and steamed pieces of Rhei Radix et Rhizoma extract in constipation rats

Pharmacokinetics,tissue distribution,and excretion of anthraquinones and their glucuronide metabolites from raw and steamed pieces of Rhei Radix et Rhizoma extract in constipation rats

Jing Zhang Jie Zou Peng Zhang Ping Zhou Yudi Xu Jiaxin Tian Yongqing Xiao Gang Cao Ying Liu

中医药科学（英文）2025，Vol.3Issue(3)：259-269,11.

中医药科学（英文）2025，Vol.3Issue(3)：259-269,11.DOI:10.1097/st9.0000000000000077

Pharmacokinetics,tissue distribution,and excretion of anthraquinones and their glucuronide metabolites from raw and steamed pieces of Rhei Radix et Rhizoma extract in constipation rats

Jing Zhang ¹Jie Zou ²Peng Zhang ²Ping Zhou ³Yudi Xu ²Jiaxin Tian ⁴Yongqing Xiao ²Gang Cao ⁵Ying Liu²

作者信息

1. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,China||School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou,China
2. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,China
3. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,China||Pharmacy Department,Weifang No.2 People's Hospital,Weifang,China
4. Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,China
5. School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou,China
折叠

摘要

关键词

Purgative effect/Laxative effect/Glucuronide metabolites/Disposition in vivo/Excretion route/Steaming process

Key words

Purgative effect/Laxative effect/Glucuronide metabolites/Disposition in vivo/Excretion route/Steaming process

引用本文复制引用

Jing Zhang,Jie Zou,Peng Zhang,Ping Zhou,Yudi Xu,Jiaxin Tian,Yongqing Xiao,Gang Cao,Ying Liu..Pharmacokinetics,tissue distribution,and excretion of anthraquinones and their glucuronide metabolites from raw and steamed pieces of Rhei Radix et Rhizoma extract in constipation rats[J].中医药科学（英文）,2025,3(3):259-269,11.

基金项目

This work was financially supported by the National Natural Science Foundation of China(No.81773907),the Scientific and Technological Innovation Project of the China Academy of Chinese Medical Sciences(No.CI2021A04207),the Fundamental Research Funds for the Central Public Welfare Research Institutes(Nos.ZZ13-YQ-042,ZXKT21021,ZXKT23011),and the National Training Program for Talents Inheriting Traditional Chinese Medicine Characteristic Technologies(Chinese Medicine Education Letter[2023]No.96). （No.81773907）

中医药科学（英文）

ISSN：2836-922X

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