中国中医药信息杂志2025，Vol.32Issue(10)：51-57,7.DOI:10.19879/j.cnki.1005-5304.202412514
针灸治疗慢性疲劳综合征随机对照试验结局指标现状分析
Analysis on the Current Situation of Outcome Indicators in Randomized Controlled Trials of Acupuncture Treatment for Chronic Fatigue Syndrome
摘要
Abstract
Objective To study the current status of the randomized controlled trial(RCT)outcome indicators of acupuncture and moxibustion in the treatment of chronic fatigue syndrome(CFS);To provide guidance and references for clinical research and protocol design.Methods RCT of acupuncture and moxibustion for CFS were retrieved from CNKI,Wanfang Data,VIP,SinoMed,PubMed,Embase,Web of Science databases from January 1,2015 to December 9,2024.Through literature screening and data extraction,Excel 2019 was used to make a descriptive analysis of the basic characteristics,diagnostic criteria,intervention measures,classification of outcome indicators,use frequency and evaluation time points of the included studies.Origin2021 software was used to draw bubble charts for visual display.Results Totally 119 RCT were included,involving 8 445 subjects,5 diagnostic criteria of Western medicine,5 diagnostic criteria of TCM,and 6 outcome indicators,namely clinical symptoms/signs,symptoms/syndrome of TCM,physical and chemical examination,quality of life,safety evaluation,and patient satisfaction.A total of 58 outcome indicators were reported,with a cumulative frequency of 430 times.Conclusion The RCT of acupuncture and moxibustion treatment of CFS have some problems,such as incomplete baseline assessment,lack of sample size calculation basis,high risk of bias,ignorance of primary and secondary indicators in the selection of outcome indicators,numerous indicators selection and measurement points,lack of long-term follow-up,inconsistent evaluation criteria for TCM syndrome efficacy,and insufficient attention to health economics evaluation and safety outcome indicators.关键词
针灸/慢性疲劳综合征/结局指标/现状分析Key words
acupuncture/chronic fatigue syndrome/outcome index/analysis of current situation分类
医药卫生引用本文复制引用
李粒萌,李华南,张士栋,徐楚瀚,黄莹雪,韩梅婕,苏志超,谭涛..针灸治疗慢性疲劳综合征随机对照试验结局指标现状分析[J].中国中医药信息杂志,2025,32(10):51-57,7.基金项目
国家自然科学基金(82474674) （82474674）
国家自然科学基金青年科学基金(81403493) （81403493）
