摘要
Abstract
With the rapid development of implant dentistry,increasing attention has been paid to the long-term stability and aesthetic outcomes of dental implants,among which sufficient volume and quality of soft and hard tissues are considered crucial contributing factors for successful treatment outcomes.Among the various available tissue regeneration strategies,plasmatrix,an autologous biomaterial derived from the patient's own peripheral blood,has demonstrated unique and significant clinical value in the re-generation and augmentation of both soft and hard tissues associated with dental implant therapy in recent years.This notable potential is primarily attributed to its rich content of multiple growth factors,viable cells,and a supportive fibrin scaffold,along with its excellent biocompatibility,tunable biodegradation profile,and a relatively simple and rapid preparation process that does not require complex laboratory equipment.As a result,its clinical applications have been continuously expanding across a wide range of indications.Based on a comprehensive review of the existing literature and current research evidence,this article provides an in-depth summary of the advancements in both basic science and clinical applica-tions of plasmatrix in the context of implant dentistry.Particular attention is given to its classification from a materials science perspective,underlying molecular mechanisms,biological effects in promoting tissue regeneration,and its implementation under different clinical scenarios.Furthermore,the article discusses unresolved technical challenges and existing controversies,and outlines potential future directions for re-search and technological innovation,aiming to provide robust evidence-based guidance for clinical prac-tice as well as a theoretical and methodological reference for future scientific investigations.关键词
血浆基质/牙种植体/骨增量/软组织再生/复合生物材料Key words
Plasmatrix/Dental implants/Bone augmentation/Soft tissue regeneration/Biocomposite materials分类
医药卫生
