磁共振成像2025，Vol.16Issue(10)：1-6,34,7.DOI:10.12015/issn.1674-8034.2025.10.001
穴位贴敷联合耳穴压豆对BPPV残余头晕脑自发活动的影响:一项随机对照功能磁共振成像研究
Effects of point application combined with ear point pressing on brain spontaneous activity in benign paroxysmal positional vertigo with residual dizziness:A randomized controlled functional magnetic resonance imaging study
摘要
Abstract
Objective:To observe the clinical efficacy of point application combined with ear point pressing in the treatment of benign paroxysmal positional vertigo(BPPV)patients with residual dizziness(RD)after successful canalith repositioning procedure(CRP),and explore its influence on the spontaneous brain activities of the patients.Materials and Methods:Using a prospective randomized controlled trial design,a total of 62 patients with RD who visited from July 2022 to December 2024 were randomly divided into an experimental group(EG)and a control group(CG),with 31 cases in each group.The CG was treated with betahistine,while the EG was given point application combined with ear point pressing therapy on the basis of CG.Data of scale scores and resting-state functional magnetic resonance imaging(fMRI)of the two groups before and after treatment were collected.Dizziness Handicap Inventory(DHI),Visual Analog Scale(VAS),and Hamilton Anxiety/Depression Scale(HAMA/HAMD)were included as clinical assessment indicators,and fractional amplitude of low-frequency fluctuation(fALFF)was included as the imaging assessment indicator.Results:Before treatment,there were no significant differences in scores of DHI,VAS,HAMA,and HAMD between the two groups(P>0.05).After treatment,the EG showed significantly lower scores on the DHI,VAS,HAMA,and HAMD compared to the CG(P<0.05).Compared to the baseline,the EG showed increased fALFF in the right insular cortex and decreased fALFF in the right superior occipital gyrus after treatment(P<0.05,FDR correction).Among the patients in the EG after treatment,the fALFF value of the right insular cortex was positively correlated with the DHI score(r=0.622,P=0.001),and the fALFF value of the right superior occipital gyrus was negatively correlated with the DHI score(r=-0.418,P=0.033).Conclusions:Point application combined with ear point pressing therapy might help improve the RD symptoms in BPPV patients by regulating the spontaneous functional activities of the vestibular-related brain regions and visual cortex.关键词
良性阵发性位置性眩晕/残余头晕/功能磁共振成像/磁共振成像/穴位贴敷/耳穴压豆Key words
benign paroxysmal positional vertigo/residual dizziness/functional magnetic resonance imaging/magnetic resonance imaging/point application/ear point pressing分类
医药卫生引用本文复制引用
蔡亚仙,李清,汪凤,王剑,雷明..穴位贴敷联合耳穴压豆对BPPV残余头晕脑自发活动的影响:一项随机对照功能磁共振成像研究[J].磁共振成像,2025,16(10):1-6,34,7.基金项目
Research Projects of Wuhan Municipal Health Commission(No.WZ22Z02,WX20Z41). 武汉市卫生健康委员会科研项目(编号:WZ22Z02、WX20Z41) （No.WZ22Z02,WX20Z41）
