神经损伤与功能重建2025,Vol.20Issue(10):后插1-后插1,1.DOI:10.16780/j.cnki.sjssgncj.202510015
运用生物信息学分析方法研究颅内出血
The use of bioinformatic analysis to study intracerebral hemorrhage
Ilgiz Gareev 1Ozal Beylerli 1Tatiana Ilyasova 1Andrey Mashkin 1Huaizhang Shi 1唐颖馨1
作者信息
摘要
Abstract
The integration of bioinformatics analysis into intracerebral hemorrhage(ICH)research represents a para digm shift in our approach to understanding,diagnosing,and treating this complex neurological disorder.By leveraging the power of bioinformatics,the scientific community is poised to make significant strides in combating this devastating condition,ultimately improving patient outcomes and quality of life.This study provides a comprehensive overview of the application of bioinformatics tools and techniques in elucidating the genetic,molecular,and environmental underpinnings of ICH.Through a detailed exami nation of genomic sequencing,transcriptomics,proteomics,and machine learning,we explore how these bioinformatics approaches have contributed to identifying genetic variants,understanding molecular pathways,and discovering biomarkers related to ICH.Challenges such as data complexity,integration of multi-omics data,and the translation of bioinformatics findings into clinical practice are discussed,alongside ethical considerations surrounding data privacy and patient consent.This study underscores the critical role of bioinformatics in advancing our understanding of ICH,offering insights into its patho physiology,and paving the way for personalized medicine and targeted therapeutic interventions.关键词
颅内出血/生物信息学分析/病理生理学/临床生物标志物/治疗靶点/个体化医疗Key words
Intracerebral Hemorrhage/Bioinformatics Analysis/Pathophysiology/Clinical Biomarkers/Therapeutic Targets/Personalized Medicine分类
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Ilgiz Gareev,Ozal Beylerli,Tatiana Ilyasova,Andrey Mashkin,Huaizhang Shi,唐颖馨..运用生物信息学分析方法研究颅内出血[J].神经损伤与功能重建,2025,20(10):后插1-后插1,1.