针刺治疗IVF中卵巢低反应作用机制的研究进展
Research progress on the mechanism of acupuncture in the treatment of poor ovarian response in IVF
摘要
Abstract
Poor ovarian response(POR)is an adverse reaction that is not sensitive to ovulation induction drugs in assisted re-productive technology,which is one of the important reasons leading to the failure of in vitro fertilization-embryo transfer.Howev-er,its pathogenesis is still unclear,and the treatment measures are limited and the efficacy is poor.Acupuncture is a kind of physi-cal therapy for acupoint stimulation.Recent studies have shown that acupuncture can improve low ovarian response.This article summarizes the mechanism of acupuncture in improving POR.Acupuncture can promote the pregnancy outcome of POR patients by relieving anxiety and depression,regulating hypothalamic-pituitary-ovarian axis,neuro-endocrine-immune system,mitochondri-al function,and adipose tissue,improving the histological morphology of ovary and uterus,as well as regulating signaling path-ways.However,the existing studies focus on efficacy,while the specific intervention programs and their mechanisms of action have not been reported,which needs further research.关键词
针刺/卵巢低反应/辅助生殖技术/作用机制Key words
Acupuncture/Poor ovarian response/Assisted reproductive technology/Action mechanism分类
医药卫生引用本文复制引用
劳健婷,李佾晟,胡攀伟,汪云蓝,孙薇,杨红..针刺治疗IVF中卵巢低反应作用机制的研究进展[J].海南医科大学学报,2025,31(19):1513-1520,8.基金项目
This study was supported by the National Natural Science Foundation of China(82274571),the National Natural Science Foundation of China Youth Program(82305284),the State Administration of Traditional Chinese Medicine-The Seventh National Project for Inheritors of Academic Experience of Traditional Chinese Medicine Experts(GKYS40142024017),Shanghai Municipal Science and Technology Commission(21Y11923400),the Shanghai Municipal Health Commission(202240007),and the Shanghai Medical Innovation and Development Foundation(WL-YJXYS-20220003K) 国家自然科学基金面上项目(82274571) （82274571）
国家自然科学基金青年项目(82305284) （82305284）
国家中医药管理局第七批全国老中医专家学术经验继承人项目(GKYS40142024017) （GKYS40142024017）
上海市科委科技计划项目(21Y11923400) （21Y11923400）
上海市卫生健康委员会项目(202240007) （202240007）
上海医学创新发展基金会资助项目(WL-YJXYS-20220003K) （WL-YJXYS-20220003K）
