解放军医学杂志2025，Vol.50Issue(9)：1070-1075,6.DOI:10.11855/j.issn.0577-7402.1764.2025.0902
基孔肯雅热研究进展
Research progress in Chikungunya fever
摘要
Abstract
Chikungunya fever(CHIKF)is a mosquito-borne infectious disease caused by Chikungunya virus(CHIKV)infection,which has become a significant public health threat of global concern in recent years.The acute phase of CHIKF is primarily characterized by sudden high fever,severe polyarthralgia,and rash.The disabling arthralgia may progress to chronic arthritis,with symptoms lasting for months or even years.This not only severely reduces patients'quality of life and impairs their labor capacity,but also imposes a heavy socioeconomic burden.In recent years,significant progress has been made in CHIKF-related research.This review elaborates on the latest research achievements in the fields of the disease's epidemiology,clinical manifestations,pathogenic mechanisms,immune response,diagnostic techniques,and prevention and treatment strategies,aiming to provide comprehensive and in-depth references for researchers and clinicians in relevant fields.关键词
基孔肯雅热/流行病学/发病机制/免疫学/诊断/疫苗Key words
Chikungunya fever/epidemiology/pathogenic mechanisms/immunology/diagnosis/vaccine分类
医药卫生引用本文复制引用
王冠珍,李小溪,刘妍,黄磊..基孔肯雅热研究进展[J].解放军医学杂志,2025,50(9):1070-1075,6.基金项目
This work was supported by the National Key Research and Development Program of China(2022YFC2304405) 国家重点研发计划项目(2022YFC2304405) （2022YFC2304405）
