解放军医学杂志2025，Vol.50Issue(9)：1083-1088,6.DOI:10.11855/j.issn.0577-7402.1886.2025.0627
基于扫频光学生物测量仪测量的角膜α角和κ角与晶状体倾斜角的相关性分析
Correlation of corneal α angle and κ angle with lens tilt angle using swept-source optical biometry
摘要
Abstract
Objective To investigate the correlation of corneal α angle and κ angle with lens tilt in normal human eyes using a new swept-source optical biometer.Methods A cross-sectional study was conducted,involving 303 healthy eyes(148 right eyes and 155 left eyes)of patients who visited the First Affiliated Hospital of Kunming Medical University from June to August 2024.ZW-30 swept-source optical biometer was used to collect the lens tilt angle,κ angle(distance from the corneal light reflex to the pupil center),and α angle(distance from corneal light reflex to the corneal geometric center,which is the midpoint of the horizontal white to white(WTW)diameter).The degrees(°)and directions of κ angle and α angle were calculated by the ratio of the above measurements to the anterior chamber depth(ACD)respectively.Spearman correlation analysis and linear regression analysis were employed to evaluate the correlations between the magnitude and direction of corneal α angle,κ angle and lens tilt angle.Results The magnitude and direction of corneal α angle,κ angle,and lens tilt angle in the right eye were as follows respectively:(0.54±0.19)mm(7.81°±3.88°),194.43°±39.75°;(0.27±0.23)mm(4.72°±3.90°),181.07°±79.59°;5.52°±1.67°,188.21°±25.73°.For the left eye,the corresponding values were:(0.47±0.27)mm(8.12°±5.26°),336.04°±46.64°;(0.26±0.27)mm(4.45°±4.80°),322.86°±107.79°;5.50°±1.61°,340.65°±32.84°.Spearman's correlation analysis showed that the correlation coefficients between corneal α angle and lens tilt angle in the right eye were 0.609(distance correlation)and 0.625(angle correlation),while those for κ angle were 0.559(distance correlation)and 0.578(angle correlation).In the left eye,the correlation coefficients between corneal α angle and lens tilt angle were 0.545(distance correlation)and 0.552(angle correlation),and those for κ angle were 0.377(distance correlation)and 0.395(angle correlation).In addition,the correlation coefficient between the direction of corneal α angle and the direction of lens tilt angle in the right eye was 0.343,and that for κ angle direction was 0.284;in the left eye,the correlation coefficients were 0.216(α angle direction)and 0.198(κ angle direction),all with statistical significance(P<0.05).Univariate linear regression analysis showed that lens tilt was positively correlated with both corneal α angle and Kappa angle(P<0.05).Conclusions Corneal α angle and κ angle are highly correlated with lens tilt angle in both eyes,and the correlation of corneal α angle is stronger than that of κ angle in both left and right eyes.The correlation expressed by degree(°)is better than that by distance(mm).It is recommended to refer to the corneal α angle and κ angle expressed in degrees during preoperative evaluation.关键词
晶状体/白内障/眼视觉/光学相干体层摄影术Key words
lens tilt/cataract/vision/optical coherence tomography分类
医药卫生引用本文复制引用
李仔所,何子涵,周洁,赵剑峰,罗晓玲,冯娅丽,杨晨,耿宇..基于扫频光学生物测量仪测量的角膜α角和κ角与晶状体倾斜角的相关性分析[J].解放军医学杂志,2025,50(9):1083-1088,6.基金项目
This work was supported by the National Natural Science Foundation of China(82360205),and the Reserve Talent Program for Young and Middle-Aged Academic and Technical Leaders(202405AC350057) 国家自然科学基金(82360205) （82360205）
云南省中青年学术和技术带头人后备人才项目(202405AC350057) （202405AC350057）
