江汉大学学报(自然科学版)2025,Vol.53Issue(5):78-84,7.DOI:10.16389/j.cnki.cn42-1737/n.2025.05.009
产后体重滞留增加再次妊娠罹患妊娠期糖尿病的风险
Risk Increase of Developing Gestational Diabetes Mellitus in the Second Pregnancy by Postpartum Weight Retention
摘要
Abstract
Objective To evaluate the association between postpartum weight retention(PPWR)and the risk of developing gestational diabetes mellitus(GDM)in the second pregnancy.Methods Taking the permanent puerperal women in Wuhan who second delivered a singleton from January 1,2019,to December 31,2022,the maternal basic information,prenatal examination,and delivery information were extracted from the maternal and child information system,and the relationship between PPWR and GDM during the second pregnancy was analyzed by logistic regression.Results A total of 3 518 pregnant women were included in this study,2 327 pregnant women(66.1%)had postpartum weight retention,of which 31.1%(1 095 pregnant women)had high weight retention.487 pregnant women(13.8%)had GDM in the next pregnancy.Regression analysis showed that women with high weight retention after their first delivery had a 38%increased risk of developing GDM in their second pregnancy(OR 1.38,95%CI(1.09,1.74)),after adjusting for relevant factors,this risk increased to 41%(aOR 1.41,95%CI(1.11,1.79)).Further analysis showed that among those with high weight retention in a first pregnancy,the risk of developing GDM in a second pregnancy increased by 53%(OR 1.53,95%CI(1.17,2.01);aOR 1.57,95%CI(1.19,2.06)),even if the first pregnancy did not develop GDM.Conclusion High weight retention after the primary delivery increases the risk of developing GDM in the second pregnancy,and postpartum weight management should be given high attention.关键词
产后体重滞留/再次妊娠/妊娠期糖尿病Key words
postpartum weight retention/second pregnancy/gestational diabetes mellitus分类
医药卫生引用本文复制引用
李乾玉,刘姗姗,杨蓉..产后体重滞留增加再次妊娠罹患妊娠期糖尿病的风险[J].江汉大学学报(自然科学版),2025,53(5):78-84,7.基金项目
湖北省自然科学基金项目(2018CFC855) (2018CFC855)