结核与肺部疾病杂志2025，Vol.6Issue(5)：495-515,21.DOI:10.19983/j.issn.2096-8493.20252004
肺结核与肺癌共病诊疗专家共识
Expert consensus on the diagnosis and treatment of coexistent pulmonary tuberculosis and lung cancer
摘要
Abstract
Comorbidity of pulmonary tuberculosis and lung cancer refers to the condition where the same patient is affected by both pulmonary tuberculosis and lung cancer either simultaneously or sequentially.The occurrence of such comorbidity increases the difficulty in diagnosis and differential diagnosis,easily resulting in missed diagnoses,misdiagnoses,and delayed treatment.There exist complex interactions between lung cancer chemotherapy,targeted drugs,and anti-tuberculosis drugs,which not only impair the efficacy of anti-tuberculosis and anti-tumor treatments but also significantly elevate adverse drug reactions.Hence,there is an urgent need to develop standardized diagnosis and treatment consensus through multidisciplinary collaboration to guide clinical practice.The Multidisciplinary Diagnosis and Treatment Branch of Chinese Antituberculosis Association and the National Clinical Research Center for Infectious Diseases/Shenzhen Third People's Hospital,in collaboration with Beijing Chao-Yang Hospital,Capital Medical University,Guangdong Lung Cancer Institute and other institutions,have jointly developed the Expert consensus on the diagnosis and treatment of coexistent pulmonary tuberculosis and lung cancer.This consensus elaborates on the epidemiological characteristics,clinical manifestations,diagnosis,and treatment of pulmonary tuberculosis-lung cancer comorbidity.It also addresses the screening and management of latent tuberculosis infection.Special emphasis is placed on key clinical challenges,such as drug-drug interactions,optimization of treatment regimens,and the appropriate timing of surgery and radiotherapy.The consensus provides 22 specific recommendations to support standardized and evidence-based clinical decision-making.关键词
结核,肺/肺肿瘤/共病现象/诊断/治疗应用Key words
Tuberculosis,pulmonary/Lung neoplasms/Comorbidity/Diagnosis/Therapeutic uses分类
医药卫生引用本文复制引用
中国防痨协会多学科诊疗分会,深圳市第三人民医院(国家感染性疾病临床医学研究中心),首都医科大学附属北京朝阳医院,广东省肺癌研究所,路希维,乔坤,李海潮,冯瑞娥,钟文昭..肺结核与肺癌共病诊疗专家共识[J].结核与肺部疾病杂志,2025,6(5):495-515,21.基金项目
Dalian Key Specialty(Tuberculosis)Peak Climbing Plan(21020021T000000006625) （Tuberculosis）
Shenzhen Healthcare"Three Famous"Project(SZSM202311034) （SZSM202311034）
Noncommunicable Chronic Diseases-National Science and Technology Major Project(2024ZD0529400) 大连市结核病重点专科登峰计划(21020021T000000006625) （2024ZD0529400）
深圳市医疗卫生三名工程(SZSM202311034) （SZSM202311034）
四大慢病重大专项(2024ZD0529400) （2024ZD0529400）
