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不同产地西洋参中七种主要人参皂苷的定量分析

朱姮 丁慧 王晓 李丽丽

山东科学2025,Vol.38Issue(5):1-9,9.
山东科学2025,Vol.38Issue(5):1-9,9.DOI:10.3976/j.issn.1002-4026.20240118

不同产地西洋参中七种主要人参皂苷的定量分析

Quantitative analysis of seven major ginsenoside components of Panaxquinquefolius L.from different origins

朱姮 1丁慧 1王晓 1李丽丽1

作者信息

  • 1. 齐鲁工业大学(山东省科学院)山东省分析测试中心天然产物分离提取共性技术创新与应用山东省工程研究中心,山东济南 250014||齐鲁工业大学(山东省科学院)药学院山东省高等学校天然药物活性成分研究重点实验室,山东济南 250014
  • 折叠

摘要

Abstract

Panaxquinquefolius L.is a medicine-food homology used in traditional Chinese medicine,of which ginsenosides are an important active component.The ginsenoside content of Panaxquinquefolius L.is closely related to its quality.Due to the effects of the geographical environment,the ginsenoside content of Panaxquinquefolius L.from different origins varies.Based on liquid chromatography-mass spectrometry,this study established a quantitative analysis method for seven major ginsenoside components,through which the content of 27 batches of samples from domestic and foreign origin swasanalyzed.The results showed that the contents of ginsenosides Rb1,Re,Rg1,Rd,Ro,and the pseudoginsenoside F11 were highest in the Panaxquinquefolius L.produced in Canada.The contents of the ginsenosides Rb1,Rg1,Rd,and Ro in the Panaxquinquefolius L.produced in the United States were higher than those from the three domestic production origins(Jilin,Shandong,and Liaoning province).The contents of the ginsenoside Re and the pseudoginsenoside F11 in Panaxquinquefolius L.produced in Shandong were higher than those produced in the United States.The contents of the rare ginsenoside Rg3 in the Panaxquinquefolius L.produced in Jilin and Liaoning were higher than that of the United States and Canada.This study revealed the differences in the content of seven ginsenosides in Panaxquinquefolius L.with foreign and domestic production origins,thereby providing technical support forquality control and improving quality standards for Panaxquinquefolius L.

关键词

西洋参/人参皂苷/多成分含量测定/超高效液相色谱-高分辨质谱

Key words

Panaxquinquefolius L./ginsenosides/multi-component content testing/ultra-high-performance liquid chromatography high-resolution mass spectrometry

分类

医药卫生

引用本文复制引用

朱姮,丁慧,王晓,李丽丽..不同产地西洋参中七种主要人参皂苷的定量分析[J].山东科学,2025,38(5):1-9,9.

基金项目

国家重点研发计划(2023YFC3503805) (2023YFC3503805)

济南市"高校20条"项目(202228020) (202228020)

齐鲁工业大学(山东省科学院)科教产项目(2023PY048) (山东省科学院)

山东科学

1002-4026

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