陕西医学杂志2025，Vol.54Issue(10)：1355-1359,1380,6.DOI:10.3969/j.issn.1000-7377.2025.10.010
老年原发性高血压患者心电图碎裂QRS波检出率及危险因素研究
Analysis of the detection rate and risk factors of ECG fragmentation QRS wave in elderly patients with essential hypertension
摘要
Abstract
Objective:To investigate the detection rate and risk factors of ECG fragmented QRS complex(fQRS)in elderly patients with essential hypertension.Methods:A total of 262 elderly patients with essential hyper-tension diagnosed and treated in our hospital from March 2022 to May 2024 were selected as the research subjects,and they were divided into fQRS group and non-fQRS group according to the presence or absence of fQRS on the sur-face ECG results,and the differences in clinical data between the two groups were compared,and the correlation be-tween the relevant indicators and the occurrence of fQRS was analyzed by Spearman rank correlation analysis.Multi-variate logistic regression analysis was used to analyze the factors affecting the occurrence of fQRS on ECG.Results:The detection rate of fQRS in 262 patients was 30.15％(79/262).Compared with the non-fQRS group,the fQRS group was older,had a longer course of disease,had higher systolic blood pressure,fasting blood glucose,homocys-teine,and NT-proBNP levels,higher LVEDD and E/e'levels,and lower 25(OH)D levels and E/A levels,and the differences between the two groups were statistically significant(all P＜0.05).Spearman rank correlation analysis showed that fQRS was associated with increased age(r=0.283,P＜0.05),prolonged disease duration(r=0.291,P＜0.05),increased systolic blood pressure(r=0.324,P＜0.05),increased fasting blood glucose(r=0.195,P＜0.05),homocysteine(r=0.236,P＜0.05),increased levels of NT-proBNP(r=0.267,P＜0.05),increased LVEDD(r=0.254,P＜0.05),and increased E/e'(r=0.279,P＜0.05)showed a significant positive correlation;There was a significant negative correlation with the decrease of 25(OH)D level(r=-0.259,P＜0.05)and E/A(r=-0.225,P＜0.05).Multivariate Logistic regression analysis showed that the increase of age,the increase of systolic blood pressure,the increase of homocysteine and NT-proBNP levels,the increase of E/e',and the decrease of 25(OH)D level were independently associated with the occurrence of fQRS in elderly patients with essential hyperten-sion(all P＜0.05).Conclusion:The detection rate of ECG fQRS is higher in elderly patients with hypertension,and the independent risk factors for fQRS are increasing age,increasing systolic blood pressure,increasing levels of homo-cysteine and NT-proBNP,increasing E/e',and decreasing 25(OH)D level.关键词
老年人/原发性高血压/心电图/碎裂QRS波/左心室肥厚/左心室舒张功能不全/危险因素Key words
Elderly/Essential hypertension/Electrocardiogram/Fragmentation of QRS complexes/Left ven-tricular hypertrophy/Left ventricular diastolic dysfunction/Risk factors分类
医药卫生引用本文复制引用
李彤,陆珍..老年原发性高血压患者心电图碎裂QRS波检出率及危险因素研究[J].陕西医学杂志,2025,54(10):1355-1359,1380,6.基金项目
陕西省重点研发计划项目(2023-YBSF-512) （2023-YBSF-512）
