沈阳医学院学报2025，Vol.27Issue(5)：477-481,491,6.DOI:10.16753/j.cnki.1008-2344.2025.05.005
丙泊酚联合瑞芬太尼麻醉对等离子腺样体切除术患儿的麻醉效果
Clinical efficacy of propofol combined with remifentanil anesthesia on plasma adenoidectomy in children
摘要
Abstract
Objective:To investigate the application effect of propofol combined with remifentanil for anesthesia in children undergoing plasma adenoidectomy.Methods:Clinical data of 103 children who underwent plasma adenoidectomy in our hospital from Apr 2023 to Apr 2024 were retrospectively analyzed.Children were divided into two groups according to different anesthesia schemes.Children who received propofol+ketamine anesthesia were enrolled in the control group(n=52)and children who received propofol+remifentanil anesthesia were enrolled in the study group(n=51).Hemodynamic parameters were compared between the two groups at four time points:before anesthesia(T0),immediately after extubation(T1),5 minutes after extubation(T2),and 10 minutes after extubation(T3).The pain scores(CHIPPS)of the two groups were compared at 10,20,and 30 min after extubation.Post-anesthesia evaluation of discomfort(PAED)and incidence of restlessness during recovery in children were compared.The indicators of stress response(cortisol and epinephrine)were measured preoperatively and 1 day postoperatively.Total perioperative adverse events were analyzed.Results:The recovery times for spontaneous breathing,eye-opening,and extubation in the study group were shorter than those in the control group(P＜0.05).The heart rate and mean arterial pressure level in the study group at T1-T3 were lower than those in the control group(P＜0.05).The CHIPPS scores at 10,20,and 30 min after extubation and PAED scores during the recovery period in the study group were lower than those in the control group(P＜0.05).The incidence of restlessness during the recovery period in the study group was lower than that in the control group(P＜0.05).The levels of cortisol and epinephrine in the study group were lower than those in the control group on day 1 after surgery(P＜0.05).There was no significant difference in the overall incidence of adverse reactions between the two groups(P＞0.05).Conclusion:The use of propofol combined with remifentanil in plasma adenoidectomy can effectively shorten the recovery time of anesthesia in children,enhance analgesic effects,reduce blood circulation fluctuations and stress reactions,and reduce the incidence of restlessness,with reliable safety.关键词
丙泊酚/瑞芬太尼/等离子腺样体切除术/儿童/血流动力学/苏醒期躁动Key words
propofol/remifentanil/plasma adenoidectomy/children/hemodynamics/restlessness during the recovery period分类
医药卫生引用本文复制引用
马鸣敏,王仁,王洪明,朱平平,崔贝贝..丙泊酚联合瑞芬太尼麻醉对等离子腺样体切除术患儿的麻醉效果[J].沈阳医学院学报,2025,27(5):477-481,491,6.基金项目
河南省医学科技攻关联合共建项目(No.LHGJ20229588) （No.LHGJ20229588）
