实用中医内科杂志2025，Vol.39Issue(9)：1-4,4.DOI:10.13729/j.issn.1671-7813.Z24101005
乳腺增生以Wnt/β-catenin信号通路和VEGF、bFGF为代表的微循环的机制探讨
The Mechanism of Microcirculation Represented by Wnt/β-catenin Signaling Pathway,VEGF and bFGF in Breast Hyperplasia Was Discussed
摘要
Abstract
Breast hyperplasia,as a precancerous lesion of breast cancer,has a variety of symptoms,with the main symptoms being breast lumps,breast pain that fluctuates with emotions,etc.Severe cases can seriously affect daily life.As the incidence of breast hyperplasia is increasing,the fear of cancer caused by it is also increasing in people's hearts.At the same time,the etiology and pathogenesis of breast hyperplasia have not been fully elucidated.Currently,the research on the etiology of breast hyperplasia in modern medicine is mainly focused on hormones,signaling pathways,and immunity.Hormones and signaling pathways have a mutual regulatory and influencing relationship,and are also inseparable from the microcirculation.The Wnt/β-catenin signaling pathway mediated by SFRP1 is related to the microcirculation.关键词
乳腺增生/分泌性卷曲蛋白1/Wnt/β-catenin信号通路/微循环Key words
breast hyperplasia/SFRP1/Wnt/β-catenin signaling pathway/microcirculation分类
医药卫生引用本文复制引用
刘鑫程,宋远航,谷丽艳,慕杨娜,孙朝渭,董禹何,靳帅,郑荣灿,黄诗瑶,张潇一,郭婧..乳腺增生以Wnt/β-catenin信号通路和VEGF、bFGF为代表的微循环的机制探讨[J].实用中医内科杂志,2025,39(9):1-4,4.基金项目
国家自然科学基金面上项目(81874347) （81874347）
辽宁省教育厅科学技术研究项目(L202064) （L202064）
辽宁中医药大学大学生创新创业训练计划项目(S202410162006) （S202410162006）
辽宁中医药大学大学生创新创业训练计划项目(S202310162017) （S202310162017）
