外科理论与实践2025，Vol.30Issue(4)：332-338,7.DOI:10.16139/j.1007-9610.2025.04.07
基于预后分析的肝内胆管癌肿瘤大小分型:一项回顾性多中心研究
Intrahepatic cholangiocarcinoma tumor size classification based on prognostic analysis:a retrospective multi-center study
摘要
Abstract
Objective To retrospectively analyze multicenter data from domestic sources,aiming to explore the link between intrahepatic cholangiocarcinoma(ICC)tumor size and prognosis,establishing a classification system based on tumor size.Methods Between December 2011 and September 2018,280 ICC patients from 13 hospitals were included.The tumor size prognosis cutoff was identified by the minimum P-value method,and the classification's overall survival related effectiveness was assessed by Kaplan-Meier analysis.Results All 280 patients were divided into the group of tumor maximum diameter≤4 cm and>4 cm.Tumor size was confirmed as an independent prognosis factor by multivariate COX regression analysis(HR=2.110,95%CI:1.358-3.280).Conclusions The tumor size dichotomy classification system based on the Chinese patient group can expediently predict ICC prognosis and offers an important basis for selecting post-operative individualized adjuvant therapy and follow up plans.关键词
肝内胆管癌/肿瘤大小/预后/回顾性研究Key words
Intrahepatic cholangiocarcinoma(ICC)/Tumor size/Prognosis/Retrospective Study分类
医药卫生引用本文复制引用
陈嘉倩,郭伟,李富宇,王坚,郑亚民,李敬东,程石,黄尧,曾永毅,刘红枝,孟令甜,周伟平,程张军,楼健颖,郑树国,毕新宇,王剑明..基于预后分析的肝内胆管癌肿瘤大小分型:一项回顾性多中心研究[J].外科理论与实践,2025,30(4):332-338,7.基金项目
福建省卫生健康委员会中青年科研重大项目(2021ZQNZD013) （2021ZQNZD013）
福州市卫生健康科技创新平台项目(2021-S-wp1) （2021-S-wp1）
