外科理论与实践2025，Vol.30Issue(4)：351-357,7.DOI:10.16139/j.1007-9610.2025.04.10
循环肿瘤DNA检测微小残留病灶在结肠直肠癌肝转移中的应用进展
Progression in circulating tumor DNA detection for minimal residual disease in patients with colorectal cancer liver metastasis
摘要
Abstract
As a non-invasive biomarker,circulating tumor DNA(ctDNA)can sensitively identify minimal residual disease(MRD),offering a novel approach for prognosis prediction and efficacy evaluation in patients with colorectal cancer liver metastasis(CRLM),thereby aiding in the formulation of personalized treatment strategies.This article summarized the progress in the application of ctDNA detection for MRD in CRLM and provided insights into its future directions.关键词
结肠直肠癌肝转移/循环肿瘤DNA/微小残留病灶/预后预测/疗效评估Key words
Colorectal cancer liver metastasis(CRLM)/Circulating tumor DNA(ctDNA)/Minimal residual disease(MRD)/Prognostic prediction/Efficacy evaluation分类
医药卫生引用本文复制引用
李雅琪,莫少波,彭俊杰..循环肿瘤DNA检测微小残留病灶在结肠直肠癌肝转移中的应用进展[J].外科理论与实践,2025,30(4):351-357,7.基金项目
国家自然科学基金(82473500,82372974,82203215) （82473500,82372974,82203215）
上海市科学技术委员会"扬帆计划"(22YF1408800) （22YF1408800）
