中国医疗设备2025，Vol.40Issue(10)：28-36,9.DOI:10.3969/j.issn.1674-1633.20242044
生物组织介电特性测量系统的设计与应用
Design and Application of Dielectric Property Measurement System for Biological Tissues
摘要
Abstract
Objective To design an integrated system for real-time dielectric property measurement of biological tissues based on the initial coaxial probe method,analyze the accuracy of the system in measuring the dielectric properties of tissues,and study the influence of probe pressure on the measurement of dielectric properties.Methods Based on components such as single-chip microcomputers,pressure sensors,and signal processing circuits,a reflection coefficient and probe pressure measurement device was constructed.The upper computer software with calibration and dielectric properties calculation functions was developed to display the probe pressure and dielectric property measurement tissue in real time.After the measurement system was established,the dielectric properties of methanol,n-propanol,liver phantom,glioma and normal brain tissue were measured,and the dielectric properties of the tissues measured by this system were verified based on standard parameters such as the coefficient of dispersion,average percentage error and relative difference.Results The average dispersion coefficients of the relative dielectric constant and electrical conductivity of methanol within the sweep frequency range were 0.0026 and 0.0827,respectively.The average percentage errors were 0.85%and 16.01%,respectively.The average dispersion coefficients of the relative dielectric constant and electrical conductivity of n-propanol within the sweep frequency range were 0.0028 and 0.0078,respectively.The average percentage errors were 2.43%and 14.38%,respectively.The relative differences in dielectric constants between glioma tissue and normal brain tissue at frequencies of 64,128 and 298 MHz were 57.28%,48.97%and 48.85%,respectively.The relative differences in electrical conductivity were 73.61%,69.9%and 66.26%,respectively.Conclusion This system can be used for real-time in vitro measurement of dielectric properties of biological tissues,and at the same time provides a reference for studying the influence of probe pressure on the measurement of dielectric properties.关键词
介电特性/开端同轴探头法/反射系数/压力监测/肝脏体模/脑胶质瘤Key words
dielectric properties/start the coaxial probe method/reflection coefficient/pressure monitoring/liver model/glioma分类
医药卫生引用本文复制引用
李博,韩继钧,陈为为,徐国放,任印豪,张盛昭..生物组织介电特性测量系统的设计与应用[J].中国医疗设备,2025,40(10):28-36,9.基金项目
国家自然科学基金面上项目(62271007) （62271007）
安徽省教育厅重点科研基金(2023AH040091) （2023AH040091）
安徽省转化医学研究院科研基金项目(2023zhyx-C15). （2023zhyx-C15）
