药食同源杂志2025，Vol.1Issue(4)：15-22,8.
药食同源物质防治结肠癌作用机制的研究进展
Research progress on the mechanisms of action of food-medicine homologous substances in preventing and treating colon cancer
摘要
Abstract
As a high-incidence malignant tumor of the digestive tract,colon cancer often faces challenges such as severe toxic and side effects and drug resistance in its clinical treatment.Relevant food-medicine homologous varieties,due to their multi-target action characteristics,have shown unique advantages in the field of oncology,and have attracted much attention especially in anti-colon cancer research.Such substances not only possess basic pharmacological activities like antibacterial,antioxidant,and anti-inflammatory effects,but also can exert anti-colon cancer functions through multiple mechanisms,including activating tumor cell autophagy,inhibiting proliferation,inducing apoptosis,reversing drug resistance,and regulating the tumor microenvironment.Based on their features of multi-pathway and low toxicity,relevant food-medicine homologous varieties provide new strategies for the treatment of colon cancer.This study systematically reviews the mechanisms of action of food-medicine homologous varieties in preventing and treating colon cancer,aiming to provide references and basis for promoting the research and development of new drugs and clinical application of food-medicine homologous substances.关键词
药食同源/结肠癌/中药/药理机制/细胞增殖/细胞凋亡Key words
food-medicine homology/colon cancer/Chinese medicine/pharmacological mechanisms/cell proliferation/cell apoptosis分类
医药卫生引用本文复制引用
胡孟晴,陈朝霞,周一苗,覃艳..药食同源物质防治结肠癌作用机制的研究进展[J].药食同源杂志,2025,1(4):15-22,8.基金项目
湖南省自然科学基金项目(2024JJ8163) （2024JJ8163）
湖南省中医药管理局重点项目(C2023005) （C2023005）
湖南省中医药管理局科研计划课题重点项目(201923) （201923）
2022年度天然药物资源与功能开发基金项目(2022ZYYGN06) （2022ZYYGN06）
湖南省创业训练项目(S20231266100X). （S20231266100X）
