药食同源杂志2025，Vol.1Issue(4)：34-41,8.
基于Box-Behnken响应面法优化阴香叶总黄酮和总酚酸提取工艺的研究
Optimization of extraction process for total flavonoids and phenolic acids from Yinxiangye(Cinnamomum burmannii leaves)based on Box-Behnken response surface methodology
摘要
Abstract
Objective To optimize the process parameters for microwave-assisted extraction of total flavonoids and total phenolic acids from Yinxiangye(Cinnamomum burmannii leaves),using the response surface methodology.Methods Single-factor experiments were carried out to examine the effects of ethanol concentration,microwave irradiation time,and solid-to-liquid ratio on extraction efficiency.A mathematical model was established based on the Box-Behnken design,using the yields of total flavonoids and total phenolic acids as the response variables,to identify the optimal conditions.Results The optimal extraction parameters were as follows:ethanol concentration of 78.16%,microwave irradiation time of 67.28 min,and solid-to-liquid ratio of 1:40(g/mL).Under these conditions,the extraction yields of total flavonoids and total phenolic acids reached 1.45%and 1.12%,respectively.Conclusion The extraction process parameters optimized via the response surface methodology are stable and reproducible,providing a scientific basis for the further development and utilization of the active constituents of Yinxiangye(Cinnamomum burmannii leaves).关键词
阴香叶/总黄酮/总酚酸/Box-Behnken响应面法/提取工艺Key words
Yinxiangye(Cinnamomum burmannii leaves)/total flavonoids/total phenolic acids/Box-Behnken response surface methodology/extraction process分类
医药卫生引用本文复制引用
戴玲,杨涛,祝廷辉,唐伟卓..基于Box-Behnken响应面法优化阴香叶总黄酮和总酚酸提取工艺的研究[J].药食同源杂志,2025,1(4):34-41,8.基金项目
湖南省自然科学基金联合项目(2023JJ60213). （2023JJ60213）
