现代畜牧科技Issue(10)：17-21,5.DOI:10.19369/j.cnki.2095-9737.2025.10.005
犬脂肪间充质基质细胞来源外泌体于宠物医疗的研究进展
Review on Research of Canine Adipose-derived Mesenchymal Stromal Cell-exosomes in Veterinary Medicine
摘要
Abstract
Canine adipose-derived mesenchymal stromal cell-exosomes(cAD-MSC-Exos),as biologically significant extracellular vesicles enriched with bioactive molecules(e.g.,nucleic acids,proteins,and lipids),stand out for their low immunogenicity,high stability,and cross-species therapeutic compatibility.They have become a research focus in veterinary medicine due to their unique therapeutic potential.With advances in engineered exosome modification,targeted delivery technologies,and the integration of artificial intelligence with biomaterials,cAD-MSC-Exos applications have demonstrated preliminary efficacy and are expected to drive innovation in the veterinary medical market.However,clinical translation remains constrained by underdeveloped large-scale production techniques,insufficient mechanistic understanding,and the absence of unified quality evaluation standards.Therefore,comprehensive investigation into the biological properties,mechanisms of action,isolation techniques,and clinical applications of cAD-MSC-Exos is essential to provide technical guidance for veterinary cell-based therapies.关键词
犬/基质细胞/外泌体/宠物Key words
dog/stromal cell/exosome/pet分类
农业科技引用本文复制引用
张卓炜,廖建昭,何洋,李韶清,唐兆新..犬脂肪间充质基质细胞来源外泌体于宠物医疗的研究进展[J].现代畜牧科技,2025,(10):17-21,5.基金项目
国家重点研发计划:畜禽普通病群体健康监测与保健技术产品研发与应用(2023YFD1801100) （2023YFD1801100）
