中国当代儿科杂志2025，Vol.27Issue(10)：1205-1211,7.DOI:10.7499/j.issn.1008-8830.2502050
住院患儿人偏肺病毒流行特征及重症肺炎危险因素分析
Epidemiological characteristics of human metapneumovirus and risk factors for severe pneumonia in hospitalized children
摘要
Abstract
Objective To investigate the epidemiological characteristics of human metapneumovirus(hMPV)and the risk factors for severe pneumonia in hospitalized children.Methods The epidemiological characteristics of hMPV in hospitalized children at Hebei Children's Hospital from January 2019 to December 2023 were retrospectively analyzed.The clinical data of hospitalized children with hMPV infection from April to December 2023 were included,and independent risk factors for severe pneumonia were identified through logistic regression.Results A total of 44 092 children were tested,with an hMPV positive rate of 7.30%(3 220/44 092).Children aged 3-6 years constituted the largest proportion(40.93%,1 318/3 220)among hMPV-positive cases.The detection rate varied significantly by year(P<0.001),peaking in 2022(12.35%,978/7 919).The peak season of the epidemic was winter and spring from 2019 to 2021,but shifted to spring and summer from 2022 to 2023.The proportion of co-infection was 38.70%(1 246/3 220),primarily with rhinovirus(600/1 246,48.15%),Mycoplasma pneumoniae(217/1 246,17.42%),and respiratory syncytial virus(182/1 246,14.61%).The main manifestations of hMPV pneumonia were cough,expectoration,and fever.Children with severe pneumonia were significantly younger(P<0.05).Wheezing,underlying diseases,co-infection,and younger age were identified as independent risk factors for severe pneumonia(P<0.05).Conclusions There are significant annual and seasonal differences in the epidemiological characteristics of hMPV in hospitalized children.Young age,underlying diseases,wheezing,and co-infection are independent risk factors for severe pneumonia.关键词
人偏肺病毒/流行病学/重症肺炎/危险因素/儿童Key words
Human metapneumovirus/Epidemiology/Severe pneumonia/Risk factor/Child引用本文复制引用
王祎轩,路素坤,黄坤玲,曹丽洁,褚亚娟,牛波..住院患儿人偏肺病毒流行特征及重症肺炎危险因素分析[J].中国当代儿科杂志,2025,27(10):1205-1211,7.基金项目
河北省政府资助临床医学优秀人才培养项目(2022180). （2022180）
