中国当代儿科杂志2025，Vol.27Issue(10)：1220-1226,7.DOI:10.7499/j.issn.1008-8830.2503149
儿童肺炎支原体肺炎反复发生塑型性支气管炎的危险因素分析
Risk factors for recurrent plastic bronchitis in children with Mycoplasma pneumoniae pneumonia
摘要
Abstract
Objective To identify risk factors for recurrent plastic bronchitis(PB)among children with Mycoplasma pneumoniae pneumonia(MPP).Methods The clinical data of children with MPP complicated by PB who underwent bronchoscopy at Gansu Province Maternity and Child Health Hospital between July 2023 and January 2025 were retrospectively analyzed.Patients were grouped into a single-episode PB group and a recurrent PB group according to the number of PB episodes.Multivariable logistic regression was used to identify risk factors for recurrent PB.Receiver operating characteristic(ROC)curve analysis was used to assess the diagnostic performance of individual and combined predictors.Results A total of 264 children were included;188(71.2%)had a single episode of PB and 76(28.8%)had recurrent PB.Multivariable logistic regression analysis showed that decreased serum albumin,atelectasis,and fever persisting beyond 72 hours after the initial bronchoscopy were significantly associated with recurrent PB(all P<0.05).The combination of these predictors yielded a sensitivity of 82.9%,specificity of 61.7%,and an area under the ROC curve of 0.777(95%CI:0.714-0.839),outperforming any single predictor(P<0.05).Conclusions In children with MPP complicated by PB,decreased serum albumin,the presence of atelectasis,and fever persisting beyond 72 hours after the initial bronchoscopy are associated with an increased risk of PB recurrence.In such cases,early repeat or multiple bronchoscopic interventions should be considered.关键词
肺炎支原体肺炎/塑型性支气管炎/反复发生/危险因素/儿童Key words
Mycoplasma pneumoniae pneumonia/Plastic bronchitis/Recurrence/Risk factor/Child引用本文复制引用
李万怡,王舒颖,王海珍,赵启君,张涛,王文媛,霍媛,王永军..儿童肺炎支原体肺炎反复发生塑型性支气管炎的危险因素分析[J].中国当代儿科杂志,2025,27(10):1220-1226,7.基金项目
兰州市科技发展指导性计划项目(2024-9-32) （2024-9-32）
甘肃省联合科研基金项目(24JRRA93). （24JRRA93）
