中国农业大学学报2025，Vol.30Issue(9)：64-74,11.DOI:10.11841/j.issn.1007-4333.2025.09.06
单亲优势是植物远缘杂交克服遗传不相容的关键策略
Uniparental dominance is a crucial strategy for overcoming genetic incompatibility in distant hybridization of angiosperms
摘要
Abstract
To have a deep understanding of the genetic mechanisms and adaptive significance of uniparental dominance in intergeneric and interfamilial hybrid offspring of angiosperms,relevant studies were retrieved and analyzed.The variation characteristics,genetic mechanisms,and adaptive significance of distant hybridization offspring were sorted out.The results showed that:1)The phenotypes of intergeneric and interfamilial hybrid offspring significantly bias toward one parent,while characteristics of the other recessive parent are either minimally expressed or not expressed at all,exhibiting uniparental dominance.This differs from classical genetic variation patterns observed in closely related hybridization,demonstrating non-Mendelian inheritance patterns.2)Uniparental dominance is regulated at three levels,i.e.,asymmetric chromosome elimination during early zygotic development;biased gene expression,systematic loss of recessive parent chromosomes or fragments and transcriptional silencing and differential in epigenetic modifications.3)Uniparental dominance represents an adaptive compatibility strategy for address genetic incompatibility between distant hybrid parents.The genetic material of the dominant parent plays a leading role in shaping offspring development,while the genetic material of the recessive parent is eliminated or suppressed.The harmonizes genetic incompatibility arising from distant parental interactions,avoiding hybrid conflicts that leads to sterility and lethality,thereby achieving relative genomic stability and maintaining normal development of offspring.Meanwhile,the retention of some exotic genes provides a potential gene pool for functional innovation.Systematic analysis of uniparental dominance in distant hybrid offspring helps to understand the unique variation patterns in intergeneric and interfamilial hybrids,and provides a theoretical basis for improving the efficiency of distant hybridization breeding.关键词
远缘杂交/属间杂交/科间杂交/单亲优势/遗传不相容Key words
distinct hybridization/intergeneric hybridization/interfamilial hybridization/uniparental dominance/genetic incompatibility分类
农业科技引用本文复制引用
高亦珂,吕奕..单亲优势是植物远缘杂交克服遗传不相容的关键策略[J].中国农业大学学报,2025,30(9):64-74,11.基金项目
国家自然科学基金项目(32371943) （32371943）
