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Radiomic model for preoperative prediction of mismatch repair deficiency in gastric cancer:a multicenter study integrating tumor sub-region radiomics and transcriptomics

Siwei Pan Weiwei Zhu Ke Shen Chencui Huang Jingxu Xu Lijing Wang Zaisheng Ye Zhiyuan Xu Can Hu Enze Li Guoliang Zheng Yi You Yanqiang Zhang Mengxuan Cao Ruolan Zhang Qing Yang Yizhou Wei

癌症生物学与医学（英文版）2025，Vol.22Issue(10)：1210-1217,中插1-中插11,19.

癌症生物学与医学（英文版）2025，Vol.22Issue(10)：1210-1217,中插1-中插11,19.DOI:10.20892/j.issn.2095-3941.2025.0254

Radiomic model for preoperative prediction of mismatch repair deficiency in gastric cancer:a multicenter study integrating tumor sub-region radiomics and transcriptomics

Siwei Pan ¹Weiwei Zhu ²Ke Shen ²Chencui Huang ³Jingxu Xu ³Lijing Wang ⁴Zaisheng Ye ⁵Zhiyuan Xu ¹Can Hu ¹Enze Li ²Guoliang Zheng ⁶Yi You ³Yanqiang Zhang ¹Mengxuan Cao ⁷Ruolan Zhang ²Qing Yang ²Yizhou Wei²

作者信息

1. Department of Gastric Surgery,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine(HIM),Chinese Academy of Sciences,Hangzhou 310022,China||Key Laboratory of Prevention,Diagnosis and Therapy of Upper Gastrointestinal Cancer of Zhejiang Province,Hangzhou 310022,China||Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer,Zhejiang Cancer Hospital,Hangzhou 310022,China
2. Department of Gastric Surgery,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine(HIM),Chinese Academy of Sciences,Hangzhou 310022,China
3. Department of Research Collaboration,R&D Center,Hangzhou Deepwise & League of PHD Technology Co.,Ltd,Hangzhou 311101,China
4. Department of Ultrasound,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine(HIM),Chinese Academy of Sciences,Hangzhou 310022,China
5. Department of Gastrointestinal Surgical Oncology,Clinical Oncology School of Fujian Medical University,Fujian Cancer Hospital,Fuzhou 350000,China
6. Department of Gastric Surgery,Cancer Hospital of China Medical University,Cancer Hospital of Dalian University of Technology,Liaoning Cancer Hospital & Institute,Shenyang 110042,China
7. Key Laboratory of Prevention,Diagnosis and Therapy of Upper Gastrointestinal Cancer of Zhejiang Province,Hangzhou 310022,China||Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer,Zhejiang Cancer Hospital,Hangzhou 310022,China||Department of Radiology,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine(HIM),Chinese Academy of Sciences,Hangzhou 310022,China
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摘要

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Siwei Pan,Weiwei Zhu,Ke Shen,Chencui Huang,Jingxu Xu,Lijing Wang,Zaisheng Ye,Zhiyuan Xu,Can Hu,Enze Li,Guoliang Zheng,Yi You,Yanqiang Zhang,Mengxuan Cao,Ruolan Zhang,Qing Yang,Yizhou Wei..Radiomic model for preoperative prediction of mismatch repair deficiency in gastric cancer:a multicenter study integrating tumor sub-region radiomics and transcriptomics[J].癌症生物学与医学（英文版）,2025,22(10):1210-1217,中插1-中插11,19.

基金项目

This study was supported by The National Key Research and Development Program of China(Grant no.2021YFA0910100),Healthy Zhejiang One Million People Cohort(Grant no.K-20230085),Post-doctoral Innovative Talent Support Program(Grant no.BX2023375),Lingyan Project of Zhejiang Provincial Department of Science and Technology(Grant no.2025C02059),the National Natural Science Foundation of China(Grant nos.82304946,82473489,and 82403546),Natural Science Foundation of Zhejiang Province(Grant nos.LR21H280001,LGF22H160056,ZCLQN25H1602,and LMS25H160006),Medicine and Health Science Fund of Zhejiang Province Health Commission(Grant nos.2025KY047 and 2022KY658),and Traditional Chinese Medicine Science and Technology Project of Zhejiang Provincial Health Commission(Grant no.2022ZA023). （Grant no.2021YFA0910100）

癌症生物学与医学（英文版）

ISSN：2095-3941

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