中华耳科学杂志2025,Vol.23Issue(8):953-957,5.DOI:10.3969/j.issn.1672-2922.2025.08.008
小型猪听觉皮层诱发电位P1-N1-P2波的特性研究
Characteristics of Cortical Auditory Evoked Potential P1-N1-P2 Waveforms in Miniature Pigs
摘要
Abstract
Objective To report a method for detection of cortical auditory evoked potential(CAEP)and characteristics of P1-N1-P2 waveforms in miniature pigs.Methods P1-N1-P2 waveforms were recorded in male miniature pigs with normal hearing(n=4)using tone bursts under anesthesia,including P1-N1-P2 latencies and amplitudes.Results P1-N1-P2 waves were detected in all 4(8-ears)animals(100%).The latency was 45.13±14.07 ms for P1,(96.00±10.72)ms for N1,and(135.13±13.95)ms for P2,while the amplitude was(2.21±1.04)μV for P1-N1,and(1.37±0.37)μV for N1-P2.Conclusion P1-N1-P2 waves reflect the auditory cortex function in miniature pigs and are similar to those in humans.Miniature pigs can be an animal model for studying auditory cortex function.关键词
小型猪/听皮层/听觉皮层诱发电位/P1-N1-P2/潜伏期/幅值Key words
miniature pigs/auditory cortex/cortical auditory evoked potential/P1-N1-P2/latency/amplitude引用本文复制引用
杨崇灵,唐菲,钟旻璇,郭维维,吕萍,刘军..小型猪听觉皮层诱发电位P1-N1-P2波的特性研究[J].中华耳科学杂志,2025,23(8):953-957,5.基金项目
国家自然科学基金面上项目(82371148) (82371148)