中医正骨2025，Vol.37Issue(9)：40-43,4.
骨小梁评分联合腰椎骨密度预测骨质疏松性椎体骨折的价值
Predictive value of trabecular bone score combined with lumbar bone mineral density for osteoporotic verte-bral fractures
摘要
Abstract
Objective:To investigate the predictive value of trabecular bone score(TBS)combined with lumbar bone mineral density(BMD)for osteoporotic vertebral fractures(OVFs).Methods:The medical records of 1213 subjects who underwent examination for lumbar BMD using dual-energy X-ray absorptiometry(DXA)from November 2023 to May 2024 were collected and analyzed.The included subjects were categorized into a fracture group and a non-fracture group based on the presence or absence of OVFs.The predictive value of TBS and lumbar BMD for OVFs was assessed by using the receiver operating characteristic(ROC)curve.Results:①Grouping and inter-group com-parison of baseline characteristics.Among the 1213 subjects,761 ones exhibited impaired or partially impaired bone microstructure(TBS＜1.310),and 347 ones were diagnosed with osteoporosis;additionally,389 subjects experienced OVFs(fracture group),while 824 ones did not(non-fracture group).Besides,the subjects in the fracture group were older and had a higher proportion of females compared to those in the non-fracture group,and they also demonstrated lower body mass index,TBS,and lumbar BMD(t=-10.186,P=0.000;x2=93.5 84,P=0.000;t=7.764,P=0.000;t=18.768,P=0.000;t=29.738,P=0.000).②The predictive value of TBS and lumbar BMD for OVFs.The ROC curve analysis revealed that the areas under the curve(AUC)for TBS,lumbar BMD,and the combination of both in predic-ting OVFs were 0.796,0.922,and 0.923,respectively.The AUC of TBS in predictive performance was smaller than that of lumbar BMD alone and the combination of both(Z=10.266,P=0.000;Z=-10.878,P=0.000),with no significant difference observed between lum-bar BMD alone and the combination of both(Z=-0.970,P=0.332).Conclusion:Combination of TBS with lumbar BMD has certain pre-dictive value for OVFs,and it performs better in predictive performance compared to TBS alone,but it does not exhibit any significant incre-mental predictive value for OVFs compared to lumbar BMD alone.关键词
骨质疏松性骨折/脊柱骨折/骨密度/骨小梁评分/风险/预测/ROC曲线Key words
osteoporotic fractures/spinal fractures/bone density/trabecular bone score/risk/forecasting/ROC curve引用本文复制引用
刘玉珂,张万义,候青青,孔西建,滕军燕,刘晨晨,彭媛媛,杨静,王娜,张斌青..骨小梁评分联合腰椎骨密度预测骨质疏松性椎体骨折的价值[J].中医正骨,2025,37(9):40-43,4.基金项目
河南省科技攻关项目(232102310124) （232102310124）
