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Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST / EiJ mice: Exploring splenomegaly and transcriptomic profiles

Yongzhi Hou Jianrong Ma Baoying Huang Na Li Lin Zhu Ziqing Jia Jiasen Yang Jingjing Zhang Wenjie Tan Jing Xue

Animal Models and Experimental Medicine2025，Vol.8Issue(8)：P.1376-1386,11.

Animal Models and Experimental Medicine2025，Vol.8Issue(8)：P.1376-1386,11.DOI:10.1002/ame2.70026

Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST / EiJ mice: Exploring splenomegaly and transcriptomic profiles

Yongzhi Hou ¹Jianrong Ma ¹Baoying Huang ²Na Li ¹Lin Zhu ¹Ziqing Jia ¹Jiasen Yang ¹Jingjing Zhang ¹Wenjie Tan ²Jing Xue³

作者信息

1. NHC Key Laboratory of Human Disease Comparative Medicine,National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China
2. NHC Key Laboratory of Biosafety,National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,China
3. NHC Key Laboratory of Human Disease Comparative Medicine,National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China State Key Laboratory of Respiratory Health and Multimorbidity,Key Laboratory of Pathogen Infection Prevention and Control(Peking Union Medical College),Ministry of Education,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences,Beijing,China
折叠

摘要

关键词

CAST/EiJ mice/mpox virus/signaling pathway/splenomegaly/vaccinia virus

分类

临床医学

引用本文复制引用

Yongzhi Hou,Jianrong Ma,Baoying Huang,Na Li,Lin Zhu,Ziqing Jia,Jiasen Yang,Jingjing Zhang,Wenjie Tan,Jing Xue..Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST / EiJ mice: Exploring splenomegaly and transcriptomic profiles[J].Animal Models and Experimental Medicine,2025,8(8):P.1376-1386,11.

基金项目

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences,Grant/Award Number:2023-I2M-2-001 （）

National Key Research and Development Project of China,Grant/Award Number:2022YFC2304100 and 2023YFC2309000 （）

National Natural Science Foundation of China,Grant/Award Number:82241068 and 82222041 （）

Beijing Natural Science Foundation,Grant/Award Number:Z220018。（）

Animal Models and Experimental Medicine

ISSN：2096-5451

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