首页|期刊导航|Phyton-International Journal of Experimental Botany|Hypoglycemic Lignans from Amomum tsao-ko Leaves:Their α-Glucosidase Inhibitory Mechanism Integrated In Silico and In Vivo Validation

Hypoglycemic Lignans from Amomum tsao-ko Leaves:Their α-Glucosidase Inhibitory Mechanism Integrated In Silico and In Vivo Validation

Yun Wang Xin-Yu Li Sheng-Li Wu Pianchou Gongpan Da-Hong Li Chang-An Geng

Phyton-International Journal of Experimental Botany2025，Vol.94Issue(8)：P.2563-2574,12.

Phyton-International Journal of Experimental Botany2025，Vol.94Issue(8)：P.2563-2574,12.DOI:10.32604/phyton.2025.068185

Hypoglycemic Lignans from Amomum tsao-ko Leaves:Their α-Glucosidase Inhibitory Mechanism Integrated In Silico and In Vivo Validation

Yun Wang ¹Xin-Yu Li ²Sheng-Li Wu ²Pianchou Gongpan ³Da-Hong Li ⁴Chang-An Geng²

作者信息

1. State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,650201,China Key Laboratory of Structure-Based Drug Design&Discovery,Ministry of Education,and School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang,110016,China
2. State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,650201,China University of Chinese Academy of Sciences,Beijing,100049,China
3. State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,650201,China
4. Key Laboratory of Structure-Based Drug Design&Discovery,Ministry of Education,and School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang,110016,China
折叠

摘要

关键词

Lignans/α-glucosidase inhibitors/enzyme kinetics/Amomum tsao-ko/oral starch tolerance test

分类

医药卫生

引用本文复制引用

Yun Wang,Xin-Yu Li,Sheng-Li Wu,Pianchou Gongpan,Da-Hong Li,Chang-An Geng..Hypoglycemic Lignans from Amomum tsao-ko Leaves:Their α-Glucosidase Inhibitory Mechanism Integrated In Silico and In Vivo Validation[J].Phyton-International Journal of Experimental Botany,2025,94(8):P.2563-2574,12.

基金项目

financially supported by the Yunnan Major Scientific and Technological Program(202202AE090035) （202202AE090035）

CAS Interdisciplinary Team of“Light of West China”Program(xbzg-zdsys-202405) （xbzg-zdsys-202405）

the Yunnan Fundamental Research Projects(202201AV070010,202301AS070069,202402AA310003) （202201AV070010,202301AS070069,202402AA310003）

Strategic Priority Research Program of the Chinese Academy of Sciences(XDB1230000) （XDB1230000）

the Yunnan Province Science and Technology Department(202305AH340005). （202305AH340005）

Phyton-International Journal of Experimental Botany

ISSN：0031-9457

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