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Rhein Inhibits Podocyte Ferroptosis and Epithelial-Mesenchymal Transition in Diabetic Nephropathy by Activating the SIRT1/p53/SLC7A11 Pathway

Wei Hu Dan Xiong

BIOCELL2025，Vol.49Issue(9)：P.1711-1731,21.

BIOCELL2025，Vol.49Issue(9)：P.1711-1731,21.DOI:10.32604/biocell.2025.067670

Rhein Inhibits Podocyte Ferroptosis and Epithelial-Mesenchymal Transition in Diabetic Nephropathy by Activating the SIRT1/p53/SLC7A11 Pathway

Wei Hu ¹Dan Xiong²

作者信息

1. Department of Endocrinology,The First Hospital of Hunan University of Chinese Medicine,Changsha,410007,China
2. Department of Nephrology,The First Hospital of Hunan University of Chinese Medicine,Changsha,410007,China
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摘要

关键词

Diabetic kidney disease/podocyte injury/Rhein/ferroptosis/epithelial-mesenchymal transition

分类

医药卫生

引用本文复制引用

Wei Hu,Dan Xiong..Rhein Inhibits Podocyte Ferroptosis and Epithelial-Mesenchymal Transition in Diabetic Nephropathy by Activating the SIRT1/p53/SLC7A11 Pathway[J].BIOCELL,2025,49(9):P.1711-1731,21.

基金项目

supported by the Hunan Province Natural Science Foundation Medical Industry Joint Fund(No.2024JJ9421) （No.2024JJ9421）

Clinical Medical Technology Innovation Guide Project of Hunan Province(No.2021SK51418). （No.2021SK51418）

BIOCELL

ISSN：0327-9545

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