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Paeoniflorin ameliorates depressive behaviours by modulating microbiota-gut-brain axis functions

Sha Zhang Dan Pan Siyu Chen Da Tang Hui Yang Daoqun Song Bin Yuan Jason H Huang Mingchen Jiang Fushun Wang Qiuyue Xu

General Psychiatry2025，Vol.38Issue(4)：P.268-280,13.

General Psychiatry2025，Vol.38Issue(4)：P.268-280,13.DOI:10.1136/gpsych-2024-101979

Paeoniflorin ameliorates depressive behaviours by modulating microbiota-gut-brain axis functions

Sha Zhang ¹Dan Pan ²Siyu Chen ³Da Tang ³Hui Yang ²Daoqun Song ⁴Bin Yuan ⁵Jason H Huang ⁶Mingchen Jiang ⁵Fushun Wang ⁷Qiuyue Xu²

作者信息

1. School of Nursing,Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China Department of Pediatrics,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China
2. School of Nursing,Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China
3. Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China
4. Changchun University of Chinese Medicine,Changchun,Jilin,China
5. Department of Pediatrics,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China
6. Department of Neurosurgery,Baylor Scott&White Health,Temple,Texas,USA
7. Institute of Brain and Psychological Science,Sichuan Normal University,Chengdu,Sichuan,China
折叠

摘要

关键词

metabolites/major depressive disorder mdd characterised/cognitive deficits/gut brain axis/microbiota/depression/chronic unpredictable mild stress/natural compound paeoniflorin

分类

医药卫生

引用本文复制引用

Sha Zhang,Dan Pan,Siyu Chen,Da Tang,Hui Yang,Daoqun Song,Bin Yuan,Jason H Huang,Mingchen Jiang,Fushun Wang,Qiuyue Xu..Paeoniflorin ameliorates depressive behaviours by modulating microbiota-gut-brain axis functions[J].General Psychiatry,2025,38(4):P.268-280,13.

基金项目

supported by the National Natural Science Foundation of China(No 82305144) （No 82305144）

the Jiangsu Provincial Natural Science Foundation Project for Universities(No 23KJB360004) （No 23KJB360004）

the National Natural Science Foundation Supporting Project of Nanjing University of Chinese Medicine(No XPT82305144). （No XPT82305144）

General Psychiatry

ISSN：2096-5923

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