Abstract
Objective To explore the current situation and influencing factors of bladder spasms in patients after kidney transplantation.Methods Selecting 80 kidney transplant patients admitted to the First Affiliated Hospital of Guangzhou Medical University from December 2022 to April 2024 as the research subjects,the occurrence of postoperative bladder spasm was recorded.Fifteen patients who experienced bladder spasm after surgery were included in the bladder spasm group,and the remaining 65 patients were included in the non bladder spasm group.The general demographic data,preoperative clinical data,intraoperative and postoperative conditions between two groups were compared.Incorporating bladder spasm as the dependent variable into the Logistics regression model to analyze the influencing factors of bladder spasm after kidney transplantation.Results A total of 15 out of 80 kidney transplant patients experienced bladder spasms after surgery,accounting for 18.76%.By comparing general demographic data between the bladder spasm group and the non bladder spasm group,it was found that there were no significant differences in gender,age,Body Mass Index,education level,payment methods,and household income(P>0.05).There was no significant differences in primary disease,combined basic disease,and dialysis method between the two groups(P>0.05),while there were significant differences in preoperative dialysis time and preoperative anemia between the two groups(P<0.05).Surgical time,intraoperative blood loss,postoperative urinary retention,postoperative visual analog scale score,C reactive protein,tumor necrosis factor-α,interleukin-6,alkaline phosphatase,transaminase,creatinine,urea nitrogen,cystatin C were not different between the two groups(P>0.05).The difference in the mean urine volume after seven days and urinary catheter material were significant(P<0.05).According to the results of the Logistic regression analysis,preoperative dialysis duration(95%CI:1.327-9.846,OR:3.614,P=0.012),preoperative anemia(95%CI:0.995-1.000,OR:0.997,P=0.045),catheter material(95%CI:1.498-3 199.687,OR:69.239,P=0.030),and mean urine output at seven days postoperatively(95%CI:1.058-334.543,OR:18.813,P=0.046)were identified as independent influencing factors for the occurrence of bladder spasms after kidney transplantation(P<0.05).Conclusions Renal transplant patients have a longer preoperative dialysis time,and the use of harder urinary catheter materials and lower postoperative urine output can increase the risk of postoperative bladder spasms.Therefore,it is necessary to increase nursing evaluation for high-risk patients with bladder spasms mentioned above,monitor postoperative urine output,and choose soft urinary catheters as much as possible to prevent the occurrence of bladder spasms after kidney transplantation.关键词
肾移植/膀胱痉挛/影响因素/透析时间/尿潴留/回归分析Key words
kidney transplantation/bladder spasms/influencing factors/dialysis time/urinary retention/regression analysis