广州医药2025，Vol.56Issue(9)：1277-1282,6.DOI:10.20223/j.cnki.1000-8535.2025.09.017
维生素D联合盐酸托莫西汀对ADHD患儿的效果及对其行为功能障碍和神经功能损伤的影响
The effect of vitamin D combined with atomoxetine hydrochloride on ADHD children and its impact on their behavioral dysfunction and neurological damage
谢积强 1高兴珺 1李睿1
作者信息
- 1. 福建医科大学附属南平第一医院儿科(福建 南平 353000)
- 折叠
摘要
Abstract
Objective To explore the effect of combined use of vitamin D and atomoxetine hydrochloride on children with attention deficit hyperactivity disorder(ADHD)and its impact on their behavioral dysfunction and neurological damage.Methods A total of 105 children with ADHD treated in the hospital were included from July 2023 to March 2024.They were divided into control group with 52 cases treated with atomoxetine hydrochloride,and observation group with 53 cases treated with vitamin D combined with atomoxetine hydrochloride using a computerized grouping method.The clinical efficacy,neurological function,behavioral function,and adverse reactions were observed in both groups.Results The total effective rate of the observation group(96.23%)was higher than that of the control group(78.85%)(P＜0.05).After treatment,compared with the control group,the levels of neuron-specific enolase in the observation group were significantly lower in terms of behavior,learning,physical fitness,impulsivity hyperactivity,anxiety and hyperactivity index scores(P＜0.05).The comparison of the incidence of adverse effects between the two groups was not significant(P＞0.05).Conclusions The combined use of vitamin D and atomoxetine hydrochloride has a more significant therapeutic effect on children with ADHD,which can effectively alleviate behavioral dysfunction,reduce neurological damage,and has good safety.关键词
注意力缺陷多动障碍/神经功能/盐酸托莫西汀/维生素DKey words
attention deficit hyperactivity disorder/neurological function/atomoxetine hydrochloride/vitamin D引用本文复制引用
谢积强,高兴珺,李睿..维生素D联合盐酸托莫西汀对ADHD患儿的效果及对其行为功能障碍和神经功能损伤的影响[J].广州医药,2025,56(9):1277-1282,6.
