内科理论与实践2025，Vol.20Issue(4)：316-318,3.DOI:10.16138/j.1673-6087.2025.04.10
利妥昔单抗序贯贝利木单抗治疗神经精神狼疮1例
A case of neuropsychiatric lupus successfully treated with sequential therapy of rituximab and belimumab therapy
摘要
Abstract
Neuropsychiatric lupus erythematosus(NPSLE)is a severe complication of systemic lupus erythematosus,it leads to a significantly increased mortality rate when it affects the central nervous system.Currently,there is no established standard treatment regimen for this condition.This article reports a case study of a patient with NPSLE,who primarily presented abnormal mental and behavioral and incoherent speech.Following sequential treatment with rituximab and belimumab,the patient's symptoms were relieved and laboratory imaging indicators were significantly improved,which provided a new potential therapeutic strategy for NPSLE.关键词
系统性红斑狼疮/神经精神狼疮/利妥昔单抗/贝利木单抗Key words
Systemic lupus erythematosus/Neuropsychiatric lupus erythematosus/Rituximab/Belimumab分类
医药卫生引用本文复制引用
陈雪,孙明芳,戴欢子..利妥昔单抗序贯贝利木单抗治疗神经精神狼疮1例[J].内科理论与实践,2025,20(4):316-318,3.基金项目
重庆市自然科学基金面上项目(重点项目)(CSTB2024NSCQ-KJFZZDX0049) （重点项目）
